SciTransfer
TransPharm · Project

AI-Driven Sustainable Production of Pharmaceutical Ingredients to Reduce Import Dependency

healthTestedTRL 5

Imagine if we could design medicine that breaks down naturally in water instead of lingering in the environment. This work uses AI to predict which chemical structures are 'earth-friendly' and finds faster, cleaner ways to make them in a continuous stream rather than in slow batches. It's like switching from a slow home-cook method to a high-tech automated assembly line for medicine.

By the numbers
12
partners
4
toolboxes delivered
33%
industry ratio
The business problem

What needed solving

European pharmaceutical companies rely heavily on third-country API production and struggle with high environmental footprints and non-biodegradable waste in water systems.

The solution

What was built

Four digital toolboxes containing AI predictive tools for molecule biodegradability and guidelines for continuous flow synthesis.

Audience

Who needs this

API ManufacturersPharmaceutical R&D LabsGreen Chemistry ConsultantsEnvironmental Compliance Officers
Business applications

Who can put this to work

Pharmaceutical Manufacturing
enterprise
Target: API Producer

If you are an API producer dealing with high waste and reliance on non-EU suppliers — this project developed digital toolboxes that optimize synthesis routes in continuous flow to reduce the environmental footprint.

Environmental Tech
mid-size
Target: Water Treatment Specialist

If you are a water treatment company dealing with pharmaceutical residues in surface water — this project developed predictive AI tools to identify and create biodegradable compounds that degrade more completely.

Digital Health
SME
Target: Drug Discovery Startup

If you are a biotech startup dealing with expensive trial-and-error in molecule design — this project developed AI methods to predict solubility and biodegradability before physical production begins.

Frequently asked

Quick answers

How does this affect the cost of production?

Based on available project data, the project focuses on reducing the footprint of synthesis and creating shortcuts in synthetic schemes, which typically lowers resource expenditure, though specific price reductions are not listed.

Can these processes be scaled to industrial levels?

Yes, the project specifically focuses on continuous flow and telescoped methods, which are designed for industrial efficiency and higher productivity compared to batch processing.

What is the IP or licensing model for the toolboxes?

Based on available project data, the project delivers four toolboxes consisting of digital tools and guidelines, but the specific licensing terms are not provided.

How does this help with EU environmental regulations?

The project develops a Life Cycle Assessment and predicts biodegradability to ensure pharmaceuticals meet stricter water quality and environmental standards.

When will these tools be available for commercial use?

The project period runs from 2022-06-01 to 2026-05-31, suggesting that final tools will be ready by mid-2026.

Consortium

Who built it

The project features a strong industrial base with a 33% industry ratio, including 4 SMEs. With 12 partners across 9 countries, the group balances academic research (5 universities, 3 research centers) with commercial application, ensuring the resulting AI tools and flow-chemistry methods are grounded in market reality.

How to reach the team

Contact Universiteit Gent regarding the four digital toolboxes for green API production.

Next steps

Talk to the team behind this work.

Contact us to identify which of the 4 TransPharm toolboxes fits your production line.

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