SciTransfer
THOR · Project

Robotic Manufacturing of Vascularized Human Tissues for Organ Repair and Replacement

healthPrototypeTRL 3

Imagine tiny robots acting like spiders to weave a complex web of blood vessels and cells. This web creates a living scaffold that mimics how our organs are built. By using these mini-robots, scientists can grow custom human tissue, like parts of the brain, to replace damaged organs without needing a donor.

By the numbers
3,994,150
EU Contribution in EUR
6
Consortium partners
The business problem

What needed solving

Millions of patients die waiting for organ transplants because current tissue engineering cannot create complex vascular networks or blood-brain barriers.

The solution

What was built

A working spiderbot designed to create fibrillar tissue scaffolds and a microfluidic system to host a functioning blood-brain-barrier.

Audience

Who needs this

Organ transplant clinicsNeurological drug developers3D bioprinting companiesPersonalized medicine providers
Business applications

Who can put this to work

Regenerative Medicine
SME
Target: Biotech startups focusing on organ replacement

If you are a biotech startup dealing with the lack of donor organs — this project developed a robotic manufacturing technology that creates vascularized human tissues. This allows for patient-tailored organ repair, potentially removing the need for cadaveric donors.

Pharmaceuticals
enterprise
Target: Drug discovery and toxicity testing firms

If you are a drug discovery firm dealing with the difficulty of testing brain-targeted drugs — this project developed a functioning blood-brain-barrier (BBB) on a microfluidic system. This provides a more accurate in vitro model for testing how drugs enter the brain.

Medical Device Manufacturing
mid-size
Target: 3D Bioprinting equipment manufacturers

If you are a device manufacturer dealing with the inability to create complex blood vessel networks in 3D prints — this project developed spiderbots and self-assembling fibers. This technology enables micrometric precision in positioning cells and angiogenic factors.

Frequently asked

Quick answers

What is the estimated cost or price of the technology?

Based on available project data, specific unit costs or pricing models for the tissue production are not provided.

Can this be produced at an industrial scale?

The project envisions the use of pools of bioinspired mini-robots in fully automated production plants to establish a Tissue Engineering industry.

What is the IP or licensing status?

Based on available project data, there is no specific information regarding patents or licensing agreements.

How long does it take to produce these tissues?

The project data does not specify a production timeline, but it focuses on maintaining tissues alive for long periods for transportation to clinics.

How is the technology integrated into existing clinical workflows?

The long-term vision is to produce personalized tissues in automated plants and transport them to hospitals and clinics.

Consortium

Who built it

The consortium is well-balanced for technology transfer, consisting of 6 partners across 4 countries. With a 50% industry ratio (3 industrial partners, including 2 SMEs), the project ensures that the robotic manufacturing techniques are developed with commercial scalability and industrial application in mind from the start.

How to reach the team

Contact the Universidad Politecnica de Madrid

Next steps

Talk to the team behind this work.

Contact us to explore licensing opportunities for the spiderbot technology.

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