SciTransfer
SYNTHEMA · Project

Privacy-Safe Synthetic Data Generation for Rare Blood Disease Research and AI Training

healthTestedTRL 5

Imagine you need a huge library of patient records to train a medical AI, but the books are locked in different vaults across Europe for privacy. Instead of trying to move the real books, this project creates 'fake' but statistically identical copies that look and act like real data. This allows researchers to study rare blood diseases without ever seeing a real patient's private identity.

By the numbers
70%
percentage of hematological conditions classified as rare
16
number of partners
10
number of countries involved
The business problem

What needed solving

Medical research for rare blood diseases is stalled because patient data is fragmented across isolated hospitals and locked by strict privacy laws. This makes it nearly impossible to get the large datasets required to train accurate AI models.

The solution

What was built

A federated computing infrastructure and AI pipelines that generate synthetic patient data and anonymize real records while keeping data local.

Audience

Who needs this

Rare disease pharmaceutical companiesMedical AI startupsEuropean health data registriesClinical research organizations (CROs)
Business applications

Who can put this to work

Pharmaceuticals
enterprise
Target: Drug Discovery Firm

If you are a drug discovery firm dealing with a lack of patient data for rare diseases—this project developed AI pipelines for synthetic data generation that allow you to train models on realistic datasets without violating GDPR.

HealthTech
SME
Target: AI Medical Software Developer

If you are an AI developer dealing with fragmented data silos in hospitals—this project developed a federated computing infrastructure that lets you train algorithms across multiple sites without moving raw sensitive data.

Healthcare Providers
mid-size
Target: Specialized Hematology Clinic

If you are a clinic dealing with the inability to share rare disease data due to strict privacy laws—this project developed anonymization and synthetic data tools that enable secure cross-border research collaboration.

Frequently asked

Quick answers

What is the cost or pricing for using these tools?

Based on available project data, no specific pricing or commercial cost is mentioned; however, the project outcomes are intended to be made openly available to healthcare and industry players.

Can this be scaled to an industrial level?

The project establishes a cross-border federated computing infrastructure connecting 10 countries, indicating a design intended for large-scale European deployment.

Who owns the IP and how is licensing handled?

Based on available project data, the project aims to make pipelines, standards, and data openly available to stakeholders in healthcare, academia, and industry.

How does this handle GDPR and data regulations?

It uses federated learning, secure multiparty computation, and differential privacy to ensure data is processed in a privacy-preserving fashion that complies with European regulations.

What is the timeline for implementation?

The project is active from 2022-12-01 to 2026-11-30.

Consortium

Who built it

The consortium is well-balanced for technology transfer, consisting of 16 partners across 10 countries. With a 31% industry ratio (5 companies, including 2 SMEs), there is significant commercial interest in the output. The mix of 6 universities and 5 research centers ensures the technical depth of the AI and privacy protocols is matched by practical industrial application.

How to reach the team

Contact Universidad Politecnica de Madrid

Next steps

Talk to the team behind this work.

Contact us to explore licensing the synthetic data pipelines for your rare disease research.

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