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SPIDeRR · Project

AI-Driven Early Diagnosis and Patient Stratification for Rheumatic Diseases

healthPrototypeTRL 3

Imagine trying to find the right key for a lock, but you have a hundred similar-looking keys and no map. This project builds a smart digital map that looks at a patient's symptoms and history to figure out exactly which rheumatic disease they have much faster. Instead of a long process of trial and error, it uses computer patterns to match patients with the right treatment immediately.

By the numbers
1.71 billion
people with musculoskeletal symptoms globally
24
consortium partners
The business problem

What needed solving

The journey to diagnosing rheumatic diseases is currently long and inefficient, leading to persistent disability and economic loss due to a trial-and-error approach in initial treatment.

The solution

What was built

Three clinical models: a patient symptom checker, a provider decision support tool for referrals, and a patient-patient similarity network for treatment optimization.

Audience

Who needs this

Health-tech software developersPrimary care provider networksRheumatology specialty clinicsPharmaceutical R&D departments
Business applications

Who can put this to work

Digital Health
SME
Target: Health-tech app developer

If you are a health-tech app developer dealing with high user churn due to vague symptom checkers — this project developed a patient symptom checker that uses machine learning to better categorize rheumatic complaints. This improves user accuracy and guides them toward the correct medical specialty.

Healthcare Services
mid-size
Target: Primary care clinic network

If you are a clinic network dealing with inefficient referral rates and long diagnostic delays — this project developed a decision support tool for providers. It provides guidance on additional examinations and referral decisions to reduce the trial-and-error approach in initial treatment.

Pharmaceuticals
enterprise
Target: Drug development company

If you are a pharma company dealing with broad patient groups in clinical trials — this project developed a patient-patient similarity network. This allows for the optimization of diagnostic groups, helping to identify which specific patient subgroups respond best to different therapies.

Frequently asked

Quick answers

What is the cost or pricing for these tools?

Based on available project data, specific pricing or licensing costs for the clinical models are not provided.

Can this be scaled to an industrial level?

The project includes federated learning pipelines and a GDPR compliant digital research environment, which are designed to support data integration across different healthcare levels in Europe.

How is the IP and licensing handled?

Based on available project data, the specific IP and licensing terms are not disclosed, though the project aims to publish analysis protocols.

How does it integrate with existing medical records?

It integrates data from primary care, secondary care, and online patient advice using federated learning to maintain privacy.

What is the timeline for deployment?

The project runs from 2023-05-01 to 2028-04-30, suggesting that final validated models will be available toward 2028.

Consortium

Who built it

The consortium is heavily weighted toward academic and research institutions (14 out of 24 partners), indicating a strong focus on scientific validation. However, there is a significant industrial presence with 4 companies (17% ratio), including 4 SMEs, which suggests a clear path toward commercializing the resulting decision support tools and symptom checkers.

How to reach the team

Contact Academisch Ziekenhuis Leiden for inquiries regarding the SPIDeRR analysis protocols.

Next steps

Talk to the team behind this work.

Contact us to track the development of these clinical models for your health-tech roadmap.

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