SciTransfer
SIMPLI-DEMO · Project

Continuous Modular Production System for Specialty Chemicals and Pharmaceuticals

manufacturingPilotedTRL 7

Imagine switching from baking one cake at a time in a big oven to a continuous conveyor belt of perfectly baked treats. Instead of stirring giant vats by hand, this system uses sound waves and microwaves to mix and heat chemicals instantly and precisely. It allows factories to make high-value plastics and medicines in a steady stream rather than in slow, separate batches.

By the numbers
9,406,833
EU Contribution in EUR
7
Target TRL level
13
Total consortium partners
The business problem

What needed solving

Specialty chemical and pharma production relies on batch-type processes with poor heat transfer and mixing control. This leads to inefficiencies, higher waste, and a lack of flexibility in production.

The solution

What was built

A pilot-scale prototype for continuous modular flow operation. It combines Reactive Extrusion (REX) and Continuous Oscillatory Baffled Reactors (COBR) with ultrasound and microwave energy.

Audience

Who needs this

Specialty chemical manufacturersPharmaceutical API producersPolymer and plastic resin developersIndustrial catalyst producers
Business applications

Who can put this to work

Pharmaceuticals
enterprise
Target: Drug manufacturer

If you are a drug manufacturer dealing with poor process control in batch-type production — this project developed a modular flow technology that enables continuous production of high-value products. This shift improves consistency and sustainability in synthesis.

Specialty Polymers
mid-size
Target: Polymer producer

If you are a polymer producer dealing with viscous products that are hard to mix — this project developed a system combining reactive extrusion and ultrasound that handles thick streams. It moves the process from TRL5 to TRL7 for industrial demonstration.

Coatings and Paints
SME
Target: Chemical coatings manufacturer

If you are a coatings manufacturer dealing with inefficient heat transfer in large tanks — this project developed microwave-actuated flow reactors. This allows for localized heating and faster, more sustainable production of particles and resins.

Frequently asked

Quick answers

What is the cost or price of implementing this system?

Based on available project data, the specific commercial price is not listed, though the EU provided a contribution of EUR 9,406,833 for the development and demonstration phase.

At what scale is this technology being demonstrated?

The project is demonstrating the first pilot-scale system prototype designed for long-term uninterrupted modular flow operation of solids-laden and viscous process streams.

How is the IP and licensing handled for these modular systems?

Based on available project data, specific licensing terms are not provided, but the consortium includes 2 technology suppliers and 4 end-user chemical companies to facilitate exploitation.

How does this integrate with existing factory automation?

The project includes a dedicated SME experienced in modular automation to ensure the continuous flow equipment integrates into industrial environments.

What is the timeline for reaching full industrial deployment?

The project runs from 2022-10-01 to 2026-09-30, with the goal of advancing the technology from TRL5 to TRL7 by the end of the period.

Consortium

Who built it

The consortium is heavily weighted toward industrial application, with an industry ratio of 62%. It consists of 13 partners, including 8 industry players (4 end-users and 2 technology suppliers) and 4 universities, ensuring that the transition from lab-scale research to a TRL7 industrial demonstration is supported by actual market users and automation experts.

How to reach the team

Contact Katholieke Universiteit Leuven regarding the SIMPLI-DEMO pilot results.

Next steps

Talk to the team behind this work.

Contact us to connect with the SIMPLI-DEMO consortium for pilot integration.

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