Imagine using tiny biological machines to build materials instead of harsh chemicals. This project creates tougher versions of these machines to turn plant waste and oils into high-value plastics and glues. It's like upgrading a delicate tool into a heavy-duty industrial power tool that can survive a factory floor.
Industrial oxidative enzymes are currently scarce compared to hydrolytic ones, and existing versions often lack the robustness to survive harsh factory conditions. This limits the production of bio-based plastics and resins.
A computational pipeline for enzyme design and pilot-scale recombinant versions of UPO, laccase, and HMFO enzymes.
If you are a panel manufacturer dealing with expensive or toxic glues — this project developed laccase-modified lignins that create 100% bio-based resins for adhesives. This increases the commercial value of existing lignin products.
If you are a plastic producer dealing with the high cost of chemical catalysts — this project developed HMFO enzymes that synthesize 2,5-furandicarboxylic acid from sugar derivatives. This provides a sustainable alternative to traditional chemical processes.
If you are a chemical company dealing with complex oxygenation reactions that are hard to synthesize — this project developed UPO enzymes for regio-selective oxygenation of lipophilic substrates. This allows for the production of high-value intermediate chemicals.
Based on available project data, specific pricing is not provided, but the project aims to develop more efficient and sustainable processes to reduce costs compared to chemical catalytic processes.
Yes, the project specifically aims to produce the best enzyme candidates at pilot scale as recombinant enzymes using customized microbial hosts.
Based on available project data, the project involves 4 SMEs and 4 research centers working on exploitation, but specific licensing terms are not detailed in the summary.
The project runs from 2024-01-01 to 2027-12-31, indicating that pilot demonstrations and optimized variants will be developed by the end of 2027.
The project focuses on conferring robustness to enzymes so they can operate under demanding industrial operating conditions, making them easier to integrate into existing chemical workflows.
The consortium is well-balanced for commercialization, featuring a 44% industry ratio with 4 SMEs (Metgen, Gecco, bisy, and InnoSyn) and 4 research/technological centers. This structure ensures that the high-level computational design from universities is immediately tested and scaled by industrial partners across 6 European countries.
Contact AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS in Spain
Contact us to connect with the ROBUSTOO consortium for pilot enzyme testing.
