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PsyPal · Project

Psilocybin Therapy System for Psychological Distress in End-of-Life Care

healthTestedTRL 5

Imagine a mental reset button for people facing the end of their lives with severe anxiety or depression. This project uses a controlled dose of a psychedelic compound to help patients find peace when standard medicines fail. It's like providing a guided emotional journey to ease the heaviest burdens of terminal illness.

By the numbers
20
partners
8
countries
4
clinical trial countries
15%
industry ratio
The business problem

What needed solving

Palliative care patients with COPD, ALS, and MS suffer from severe psychological distress that current drugs cannot treat. This creates a gap in care that reduces quality of life for patients and families.

The solution

What was built

A standardized therapy manual, a digital care platform, and a GMP-certified drug delivery system for psilocybin.

Audience

Who needs this

Palliative care providersPsychiatric clinicsPharmaceutical companies specializing in CNSDigital health startups
Business applications

Who can put this to work

Pharmaceuticals
enterprise
Target: Specialized drug manufacturer

If you are a drug manufacturer dealing with the lack of effective treatments for end-of-life anxiety — this project developed a standardized therapy manual and GMP-certified drug delivery process that ensures patient safety and consistent results.

Digital Health
SME
Target: Health-tech platform provider

If you are a tech provider dealing with fragmented post-treatment care — this project developed a digital care platform and peer-support networks that maintain patient wellbeing after the clinical session.

Healthcare Services
mid-size
Target: Private palliative care clinic

If you are a clinic owner dealing with high patient distress in COPD or ALS cases — this project developed a trained therapist model and clinical protocol that can be integrated into care services to improve quality of life.

Frequently asked

Quick answers

What is the cost or price of this therapy?

Based on available project data, specific pricing is not mentioned, but the project aims to create a cost-effective deployment model for European healthcare systems.

Can this be scaled to an industrial level?

The project uses a multi-centre trial across 4 countries and GMP-certified drug manufacturing, suggesting a scalable clinical model.

What are the IP and licensing options?

Based on available project data, specific patents are not listed, but the project has produced a standardized therapy manual and a digital care platform.

What regulatory hurdles have been cleared?

The project has secured full regulatory and ethical approval in the Netherlands, Denmark, Portugal, and the Czech Republic.

What is the timeline for implementation?

The project runs from 2024-01-01 to 2027-12-31, with the first 18 months focused on establishing the operational foundation.

Consortium

Who built it

The consortium is heavily weighted toward clinical and academic expertise, featuring 20 partners across 8 countries. With 6 universities and 3 research centers, the focus is scientific validation, though the inclusion of 3 SMEs and a 15% industry ratio indicates a clear path toward commercial translation and practical application in healthcare settings.

How to reach the team

Contact Academisch Ziekenhuis Groningen in the Netherlands

Next steps

Talk to the team behind this work.

Contact us to explore licensing the therapy manual or digital platform.

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