SciTransfer
PRISM-LT · Project

3D Bioprinting Platform for Lab-Grown Tissues and Cultured Meat

manufacturingTestedTRL 4

Imagine a 3D printer that doesn't just use plastic, but living cells. To make these cells grow into complex shapes like bone or steak, the project adds 'helper' cells—like tiny biological factories—that feed the main cells exactly what they need at the right moment. It's like having a smart construction crew that builds the scaffolding and provides the fuel simultaneously.

By the numbers
7
total deliverables
5
countries involved
The business problem

What needed solving

Current 3D bioprinting lacks the speed and scale for commercial use and struggles to guide stem cells to form complex, functional tissues naturally.

The solution

What was built

A bioprinting platform using 'symbiotic materials' consisting of stem cells and engineered helper cells (bacteria/yeast) that automatically trigger growth factors.

Audience

Who needs this

Cultured meat producersPharmaceutical drug-screening labsTissue engineering biotech firmsMedical device manufacturers
Business applications

Who can put this to work

Biomedical Research
enterprise
Target: Pharmaceutical R&D labs

If you are a drug developer dealing with the inaccuracy of 2D cell cultures—this project developed a platform for organoids as in-vitro models that provides more predictable and complex living tissue structures for testing.

Alternative Proteins
SME
Target: Cultured meat startups

If you are a food tech company dealing with the difficulty of creating realistic meat textures—this project developed a method to cultivate marbled cultured meat using engineered yeast to promote muscle and fat growth.

Regenerative Medicine
mid-size
Target: Medical implant manufacturers

If you are a biotech firm dealing with the challenge of growing functional bone tissue—this project developed engineered bacterial helper cells that secrete growth factors to support bone formation.

Frequently asked

Quick answers

What is the cost of implementing this bioprinting platform?

Based on available project data, specific pricing or cost structures for the platform are not provided.

Can this process be scaled to industrial levels?

The project explicitly aims to overcome challenges regarding controlled printability on a commercially viable scale and speed.

What IP or licensing options are available for the helper cells?

Based on available project data, specific licensing terms are not mentioned, though the project has developed proprietary engineered E. coli and yeast strains.

How does the system integrate with existing stem cell workflows?

The platform integrates stem cells into a support matrix enriched with helper cells that respond to metabolites secreted by the stem cells during differentiation.

What is the timeline for market availability?

The project period runs from 2022-11-01 to 2027-10-31, suggesting it is currently in the development and testing phase.

Consortium

Who built it

The consortium is well-balanced for technology transfer, consisting of 7 partners with a 43% industry ratio (3 companies, including 2 SMEs). The collaboration between 4 universities and industry players across 5 countries suggests a strong pipeline from academic research to commercial application.

How to reach the team

Contact IN SRL in Italy

Next steps

Talk to the team behind this work.

Contact us to explore licensing opportunities for symbiotic bio-inks.

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