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PeptiCHIP · Project

Rapid Microfluidic Platform for Personalized Cancer Immunotherapy Target Identification

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Imagine trying to find a specific needle in a haystack, where the needle is a unique protein on a cancer cell. Current methods are like searching by hand for days using expensive tools. This technology acts like a high-powered magnet and a smart filter, quickly pulling out the exact targets needed to create a custom-made medicine for a patient.

By the numbers
60-80%
Patient failure rate in current cancer immunotherapies
The business problem

What needed solving

Current neoantigen identification is too slow, expensive, and complex, limiting personalized immunotherapy to a few elite labs. This results in 60-80% of patients not responding to treatment.

The solution

What was built

A microfluidic immunopurification device combined with a peptide prioritization algorithm and mass spectrometry integration.

Audience

Who needs this

Personalized cancer vaccine developersClinical oncology labsAutoimmune disease researchersProteomics service providers
Business applications

Who can put this to work

Biopharmaceuticals
any
Target: Immunotherapy developers

If you are an immunotherapy developer dealing with the fact that 60-80% of patients fail to respond to treatment — this project developed a microfluidic device and software that identifies the most relevant neoantigens to increase the chance of success.

Clinical Diagnostics
mid-size
Target: Precision medicine clinics

If you are a clinic dealing with long and resource-demanding antigen identification processes — this project developed PeptiCHIP which provides rapid, accurate results using minimal sample amounts and lower costs.

Biomedical Research
any
Target: Academic and private research institutes

If you are a research institute dealing with the lack of standard methods to identify antigens for autoimmune or infectious diseases — this project developed a platform that identifies relevant antigens without needing prior knowledge of their sequences.

Frequently asked

Quick answers

How does this affect the cost of neoantigen identification?

Based on available project data, PeptiCHIP is designed to be low-cost and reduces the need for expensive laboratory equipment and consumables compared to current resource-demanding methods.

Can this be scaled for industrial use?

The project is currently in the pre-clinical validation and demonstration phase to generate evidence for investors and create a transition-to-market plan.

Who owns the intellectual property and is it available for licensing?

The IP was protected following a Proof of Concept at the University of Helsinki, and Valo Therapeutics holds full rights to develop, exploit, and commercialize the technology.

What is the timeline for clinical availability?

The project period runs from 2023-04-01 to 2025-09-30, focusing on pre-clinical validation and the transition-to-market plan.

How does this integrate with existing lab workflows?

PeptiCHIP integrates a microfluidic purification device with mass spectrometry analysis and a specific prioritization software to simplify the antigen profiling process.

Consortium

Who built it

The project is led by a single partner, Valo Therapeutics OY, a Finnish SME. With a 100% industry ratio, the project is streamlined for commercial exploitation, moving directly from a university-proven concept to a business-led pre-clinical validation phase.

How to reach the team

Contact Valo Therapeutics OY in Finland

Next steps

Talk to the team behind this work.

Contact us to explore licensing opportunities for PeptiCHIP technology.

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