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PANGenS · Project

Genomic Surveillance Network for Tracking Drug-Resistant Diseases in Africa

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Imagine a high-tech GPS for germs that tells us exactly where a disease is moving and how it's changing. By reading the genetic code of bacteria and parasites, scientists can spot when medicines stop working before it becomes a crisis. It's like having an early warning system to stop outbreaks in their tracks.

By the numbers
13
partners
11
countries
24
total deliverables
The business problem

What needed solving

African health systems struggle with fragmented data and limited genomic capacity, making it difficult to track drug-resistant TB and malaria or respond quickly to new pathogens.

The solution

What was built

Developed SeqSphere+ software for core genome MLST analysis and established standard operating protocols for next-generation sequencing and bioinformatics.

Audience

Who needs this

IVD (In Vitro Diagnostics) companiesAnti-infective pharmaceutical companiesPublic health surveillance agenciesBioinformatics software developers
Business applications

Who can put this to work

Diagnostics
enterprise
Target: Medical device manufacturer

If you are a medical device manufacturer dealing with outdated TB tests — this project developed genomic data on drug-resistant strains that allows for the creation of more sensitive and specific rapid diagnostics.

Pharmaceuticals
enterprise
Target: Antimalarial drug developer

If you are an antimalarial drug developer dealing with emerging drug resistance — this project developed a regional surveillance system that provides pre-emptive detection of resistant parasites to guide R&D.

Bioinformatics
SME
Target: Health data software provider

If you are a health data software provider dealing with fragmented African health data — this project developed SeqSphere+ and harmonized analysis tools to identify cross-border spread of pathogens.

Frequently asked

Quick answers

What is the cost or pricing for using these tools?

Based on available project data, there is no information regarding the cost or pricing of the developed tools.

Is this system ready for industrial scale?

The project is currently in the proof-of-concept stage, focusing on establishing infrastructure and training across 11 countries to build capacity for future scaling.

What are the IP and licensing terms for the software?

Based on available project data, specific IP or licensing terms for SeqSphere+ and other tools are not mentioned.

How does this integrate with existing health systems?

The project focuses on creating harmonized genomic data analysis tools and biobanking to allow for continent-wide surveillance networks.

What is the timeline for the results?

The project period runs from 2023-07-01 to 2027-06-30, with initial workshops and infrastructure assessments completed in 2024.

Consortium

Who built it

The consortium is heavily research-oriented, consisting of 13 partners from 11 countries, including 7 research institutes and 5 universities. There are 0 industry partners and 0 SMEs, indicating that the project is currently in a pre-commercial, academic phase focused on capacity building and infrastructure in Africa.

How to reach the team

Contact Forschungszentrum Borstel Leibniz Lungenzentrum in Germany.

Next steps

Talk to the team behind this work.

Contact us to explore licensing opportunities for SeqSphere+ or genomic data partnerships.

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