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ORIGIN · Project

AI-Driven Platform for Rapid Production of High-Value Natural Ingredients via Precision Fermentation

manufacturingTestedTRL 5

Imagine if we could grow rare plant ingredients in a lab instead of digging them up from the wild. This project uses a giant digital library of nature's DNA and an AI 'automated scientist' to figure out the recipe for these molecules. It then teaches microbes to brew these ingredients in tanks, making the process much faster and kinder to the planet.

By the numbers
10 billion
sequences in metagenomic database
50
AI-optimized pathway blueprints for molecules
10
validated microbial strains
3
molecules demonstrated at pilot scale
10 g/L
minimum titers achieved
95%
minimum purity
90%
reduction in land use
30-50%
reduction in GHG emissions
The business problem

What needed solving

High-value natural ingredients currently rely on unsustainable wild harvesting, which threatens biodiversity and creates fragile, slow supply chains that take up to a decade to develop new products.

The solution

What was built

An end-to-end bioproduction platform featuring an LLM-based 'automated scientist' (ORIGIN Co-pilot) and a metagenomic database of 10 billion sequences.

Audience

Who needs this

Cosmetic ingredient suppliersNutraceutical manufacturersPharmaceutical R&D firmsFragrance and Flavor (F&F) houses
Business applications

Who can put this to work

Cosmetics
enterprise
Target: Premium skincare brand

If you are a premium skincare brand dealing with unstable supplies of rare botanical extracts — this project developed an AI-powered bioproduction platform that reduces time-to-market from 5–10 years to 2–3 years. This ensures a steady, sustainable supply of high-purity ingredients without harming biodiversity.

Nutraceuticals
mid-size
Target: Health supplement manufacturer

If you are a health supplement manufacturer dealing with the high cost and environmental impact of wild-harvesting species like Panax ginseng — this project developed a precision fermentation system that cuts land use by >90%. It allows for the industrial generation of ingredients with >95% purity.

Pharmaceuticals
enterprise
Target: Drug discovery and development firm

If you are a drug discovery firm dealing with slow and fragmented pipelines for natural product synthesis — this project developed an AI-driven retrosynthesis and host-aware pathway design tool. This accelerates the delivery of validated microbial strains and optimized pathway blueprints for 50 molecules.

Frequently asked

Quick answers

What is the expected cost or price reduction?

Based on available project data, specific price points are not listed, but the project aims to reduce development time from 5–10 years down to 2–3 years, significantly lowering R&D overhead.

At what industrial scale will the ingredients be produced?

The project will demonstrate 3 molecules at a pilot scale ranging from 30L to 100L, achieving titers greater than 10 g/L.

How is the IP and licensing handled for the genetic data?

The project leverages a proprietary, Nagoya-compliant metagenomic database containing over 10 billion sequences to ensure legal and ethical sourcing of genetic information.

What is the timeline for bringing a new molecule to market?

The platform aims to reduce the current time-to-market for bio-based ingredients from 5–10 years to just 2–3 years.

How does this integrate into existing manufacturing?

It uses a multi-host rapid prototyping approach across common industrial microbes like E. coli and S. cerevisiae, making it compatible with standard fermentation infrastructure.

Consortium

Who built it

The consortium is well-balanced for commercialization, featuring a 43% industry ratio with 3 industrial partners and 2 SMEs. With 7 partners across 6 countries (including the UK, NL, and PT), the project combines academic research from 3 universities with the operational capacity of SILICOLIFE SA to move from digital design to pilot-scale production.

How to reach the team

Contact SILICOLIFE SA in Portugal for partnership opportunities regarding the ORIGIN Co-pilot AI.

Next steps

Talk to the team behind this work.

Contact us to identify which of the 50 target molecules align with your product pipeline.

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