SciTransfer
OPADE · Project

AI-Driven Personalized Antidepressant Prescription Tool Using Multi-Omics Biomarkers

healthTestedTRL 5

Imagine if your doctor could tell exactly which antidepressant will work for you by looking at your gut bacteria and genes, rather than using trial and error. This project builds a smart tool that connects brain activity and biological markers to predict drug success. It's like a personalized GPS for mental health treatment to avoid the long road of ineffective medications.

By the numbers
280M
people worldwide suffering from major depressive disorders
6%
patients who benefit from the current therapeutic journey
350
patients recruited for the study
The business problem

What needed solving

Current antidepressant treatments have a very low success rate, with only 6% of patients achieving remission. Doctors lack the biomarkers needed to choose the right drug for the right patient the first time.

The solution

What was built

An AI/ML predictive tool for antidepressant efficacy and a patient empowerment Chatbot for data collection.

Audience

Who needs this

Precision medicine pharmaceutical companiesPsychiatric diagnostic clinicsDigital health monitoring companiesClinical research organizations (CROs)
Business applications

Who can put this to work

Pharmaceuticals
enterprise
Target: Drug Development Company

If you are a drug developer dealing with low remission rates—currently not more than 6% of patients benefit from the therapeutic journey—this project developed an AI/ML predictive tool that identifies new molecular targets for personalized treatment.

Digital Health
SME
Target: Health-Tech Startup

If you are a tech provider dealing with poor patient adherence in mental health—this project developed a patient empowerment Chatbot that translates patient stories into usable data for clinicians.

Diagnostics
mid-size
Target: Clinical Laboratory

If you are a lab dealing with a lack of early biomarkers for depression—this project developed a multi-omics analysis method covering metagenomics and epigenomics to improve diagnostic accuracy.

Frequently asked

Quick answers

What is the cost or pricing for the AI tool?

Based on available project data, there is no information regarding the pricing or cost of the predictive tool.

Can this be scaled to a global industrial level?

The project is already testing across 10 countries and recruiting 350 patients from 6 different countries, suggesting a design intended for international scalability.

What are the IP and licensing terms for the ML algorithm?

Based on available project data, specific IP and licensing terms are not disclosed in the project summary.

How long does the development timeline last?

The project period runs from 2022-12-01 to 2027-05-31.

How is the tool integrated into clinical workflows?

The tool integrates real-time EEG, cognitive assessments, and biological samples (blood, stool, saliva) to support the decision-making process of healthcare providers.

Consortium

Who built it

The consortium is well-balanced for commercialization, featuring 14 partners across 10 countries. With a 36% industry ratio (5 industrial partners, 5 of which are SMEs), there is a strong bridge between the 3 universities and 3 research centers and the actual market, ensuring the AI tool is developed with commercial viability in mind.

How to reach the team

Contact Fondazione EBRIS in Italy for partnership inquiries.

Next steps

Talk to the team behind this work.

Contact us to explore licensing opportunities for the OPADE AI predictive tool.

More in Health & Biomedical
See all Health & Biomedical projects