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NanoWi · Project

High-Sensitivity Nanowire Sensors for Faster and Cheaper Disease Biomarker Detection

healthPilotedTRL 9

Imagine trying to find a needle in a haystack, but the needle is a tiny molecule in your blood. Current tools often miss these markers because they are too few or the signal is too weak. This technology uses tiny 3D 'nanowires' that act like high-powered antennas to catch and amplify these signals, making them much easier to spot.

By the numbers
20
times increase in sensitivity over current assays
90%
minimum alignment of nanowires over 1mm2
The business problem

What needed solving

Current biomarker assays lack the sensitivity for multiplexing and have weak signal-to-noise ratios. Additionally, existing 3D nanowire platforms are too expensive and difficult to produce reproducibly at scale.

The solution

What was built

A beta production tool (ATXY) and a method to produce vertically aligned GaP and Si nanowires in polymer films on a large scale.

Audience

Who needs this

Cancer diagnostic companiesMedical sensor manufacturersPrecision medicine laboratoriesBiotech assay developers
Business applications

Who can put this to work

Clinical Diagnostics
enterprise
Target: Diagnostic Lab Provider

If you are a diagnostic lab provider dealing with late-stage cancer detection due to low biomarker concentrations — this project developed 3D NW-platforms that provide a 20-times increase in sensitivity. This allows for earlier diagnosis and improved patient survival rates.

Medical Device Manufacturing
mid-size
Target: Point-of-Care Device Manufacturer

If you are a device manufacturer dealing with the high cost of producing reproducible biosensors — this project developed Aerotaxy™ production technology. It enables mass-scale, cost-effective production of aligned nanowires for commercial viability.

Pharmaceuticals
enterprise
Target: Precision Medicine R&D Firm

If you are an R&D firm dealing with weak signal-to-noise ratios in multiplexed biomarker assays — this project developed sensors with optical waveguiding properties. This results in signals more than an order of magnitude higher than planar platforms.

Frequently asked

Quick answers

How does this affect the cost of biomarker detection?

The project utilizes proprietary Aerotaxy™ technology to ensure that nanowire sensors can be produced at a cost that makes mass-scale production feasible and low-priced.

Can this technology be scaled for industrial use?

Yes, the objective is to enable mass- and cost-effective production of nanowire sensors, specifically achieving vertical alignment of nanowires on a large scale.

What intellectual property protects this technology?

The solution relies on three core patented technologies that allow for the production of high-quality nanowires with controlled diameters.

How does the sensitivity compare to existing market solutions?

Based on available project data, these sensors offer 20 times higher sensitivity than current solutions in the market.

What is the timeline for market readiness?

The project period ran from 2022-06-01 to 2024-09-30, with the goal of bridging the risk-gap to reach TRL9.

Consortium

Who built it

The project is led by a single Swedish SME, Aligned Bio AB. This 100% industry-led consortium indicates a strong focus on commercialization and direct market entry rather than academic exploration.

How to reach the team

Contact Aligned Bio AB in Sweden regarding Aerotaxy™ licensing

Next steps

Talk to the team behind this work.

Contact us to explore partnership opportunities with Aligned Bio AB

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