If you are a dental implant manufacturer dealing with post-surgery infection complaints and implant rejection rates — this project developed nanostructured ZrTi alloy coatings using sol-gel, laser patterning, and electrospinning methods that improve osseointegration and add antibacterial properties. The consortium of 10 partners across 7 countries, including 6 SMEs, validated these surface treatment methods for implant-grade metals.
Next-Generation Dental Implants with Nano-Coated Surfaces That Fight Infection
Imagine a dental implant that bonds to your jawbone faster and fights off bacteria on its own — like a non-stick pan that also keeps germs away. This project worked on coating titanium-zirconium implants with ultra-thin layers using techniques borrowed from laser engraving and nanofiber spinning. The goal was to make implant surfaces that your body accepts more readily while preventing the infections that often follow implant surgery. Ten teams across seven countries pooled their expertise in metals, coatings, and biology to push this forward.
What needed solving
Dental implants fail too often due to poor bone integration and post-surgery bacterial infections, leading to costly revision procedures and patient suffering. Current implant surfaces lack the nano-level engineering needed to actively promote bone growth while simultaneously preventing bacterial colonization. Manufacturers need surface treatment methods that solve both problems without adding prohibitive cost or complexity to production.
What was built
The project investigated three nano-scale surface treatment methods for ZrTi dental implants: sol-gel metal oxide coatings, laser-induced periodic surface structures, and electrospinning of organic nanofiber scaffolds. Across 19 deliverables, the consortium produced research findings, characterization data, and trained researchers, with results shared through organized workshops, conferences, and public outreach activities.
Who needs this
Who can put this to work
If you run a dental implant practice dealing with post-operative complications and patient callbacks — this research developed implant surfaces designed to reduce bacterial inflammatory complications after surgery. Better bone integration means fewer revision procedures. The project ran for over 5 years with partners from Latvia, Czech Republic, Italy, Poland, Estonia, Ukraine, and the UK.
If you are a surface treatment company looking to enter or expand in the medical device market — this project advanced three distinct nano-coating techniques: sol-gel metal oxide deposition, laser-induced periodic surface structures (LIPSS), and electrospinning of organic nanofibers. These methods could diversify your coating portfolio for biomedical applications beyond dental implants.
Quick answers
What would it cost to license or adopt these surface treatment methods?
The project was funded under MSCA-RISE (a research staff exchange scheme) with EUR 1,008,000 in EU contribution, focused on knowledge transfer rather than product commercialization. Licensing terms would need to be negotiated directly with the consortium lead, Latvijas Universitate. Costs would depend on which specific technique (sol-gel, LIPSS, or electrospinning) you want to adopt.
Can these coating methods work at industrial production scale?
Based on available project data, the techniques explored — sol-gel deposition, laser patterning, and electrospinning — are established industrial processes in other sectors. However, the project's MSCA-RISE funding scheme focused on researcher mobility and knowledge exchange rather than scaling up production. Moving to industrial volume would require additional development and validation.
Who owns the intellectual property from this project?
IP generated under Horizon 2020 MSCA-RISE projects is typically owned by the institution whose researchers made the discovery. With 10 partners across 7 countries (Latvia, Czech Republic, Estonia, Italy, Poland, Ukraine, UK), IP may be distributed across multiple institutions. A licensing discussion should start with the coordinator, Latvijas Universitate.
What regulatory approvals would be needed to use these implants?
Dental implants in the EU require CE marking under the Medical Device Regulation (MDR 2017/745), including biocompatibility testing per ISO 10993 and implant-specific standards. Based on available project data, the research focused on material development and characterization rather than regulatory submission. Any manufacturer would need to run full clinical trials.
How long before these implants could reach the market?
The project closed in June 2023 after running since January 2018. As an MSCA-RISE knowledge exchange project, the outputs are research findings and trained researchers rather than market-ready products. A realistic path to market would require prototype manufacturing, preclinical testing, and clinical trials — typically adding several more years.
Can these coatings be applied to existing implant designs?
The surface modification techniques (sol-gel, laser patterning, electrospinning) are designed to be applied to implant surfaces, which suggests compatibility with existing implant geometries. Based on the project objective, the coatings were developed specifically for Zirconium-Titanium alloy substrates, so adaptation to other alloys would need validation.
Who built it
The NanoSurf consortium is unusually industry-heavy for a research mobility project, with 6 out of 10 partners (60%) being SMEs — a strong signal of commercial interest from the dental and materials sectors. The 7-country spread (Czech Republic, Estonia, Italy, Latvia, Poland, Ukraine, UK) covers both established dental implant markets and cost-competitive manufacturing bases. Latvijas Universitate coordinates from Latvia, which offers lower R&D costs. The 4 university partners provide the scientific backbone in nanotechnology and biomaterials, while the 6 industry partners likely include implant manufacturers and surface treatment specialists who could carry results toward commercialization.
- LATVIJAS UNIVERSITATECoordinator · LV
- NANOPHARMA ASparticipant · CZ
- THE UNIVERSITY OF SHEFFIELDparticipant · UK
- LINARI ENGINEERING SRLparticipant · IT
- UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIAparticipant · IT
- NANO PRIME SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIAparticipant · PL
Latvijas Universitate (University of Latvia) coordinated this project. SciTransfer can help identify the right contact person and facilitate an introduction.
Talk to the team behind this work.
Want to explore licensing these nano-coating techniques for your implant line? SciTransfer can connect you with the research team and help assess commercial fit.