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MPOX-PROBE · Project

Advanced Mpox Surveillance and Transmission Modeling for Regional Outbreak Prevention

healthTestedTRL 5

Imagine trying to stop a fire by tracking not just the flames, but also the wind and the dry grass that spreads it. This work tracks how Mpox moves between people, animals, and even the air and water in border regions. By mapping these hidden paths, it helps health teams predict where the next outbreak will hit before it happens.

By the numbers
114
countries reporting MPXV cases
89752
confirmed reports of MPXV
250
human blood samples collected
95
animal samples collected
75
wastewater samples collected
18
air samples collected
2366
individuals involved in KAP studies
The business problem

What needed solving

Public health agencies lack precise data on how Mpox spreads between animals and humans in border regions. This gap makes it impossible to predict outbreaks or deploy targeted interventions effectively.

The solution

What was built

A surveillance system combining RT-PCR diagnostics, metagenomic sequencing, and spatiotemporal risk models. It includes a database of human, animal, and environmental samples to map transmission routes.

Audience

Who needs this

Diagnostic kit manufacturersEpidemiological software developersGlobal health NGOsGovernmental public health agencies
Business applications

Who can put this to work

Diagnostics
mid-size
Target: Medical device and test kit manufacturer

If you are a test kit manufacturer dealing with low detection rates in remote areas — this project developed new diagnostics and sampling methods that identified 54 positive human cases and 9 positive air samples. This provides a blueprint for high-sensitivity field tests.

Public Health Insurance
enterprise
Target: Health insurance provider

If you are an insurer dealing with unpredictable epidemic costs — this project developed spatiotemporal risk and transmission models. These tools allow for better prediction of future outbreaks to manage risk and resource allocation.

Environmental Services
SME
Target: Wastewater monitoring company

If you are a monitoring firm dealing with the need for early warning systems — this project analyzed 75 wastewater samples to trace virus spread. This proves the viability of using sewage as a non-invasive early warning system for Mpox.

Frequently asked

Quick answers

What is the cost or price of the developed diagnostics?

Based on available project data, there is no information regarding the specific cost or pricing of the diagnostics developed.

Can these surveillance methods be scaled to an industrial level?

The project demonstrates scalability by collecting samples from 2,366 people and various environmental sources across two countries, suggesting the methods can be expanded to larger regional scales.

Are there patents or licensing opportunities for the transmission models?

Based on available project data, there is no mention of patents or specific licensing terms for the spatiotemporal risk models.

How does this integrate with existing health regulations?

The project focuses on strengthening public health response and sharing surveillance data with health workers in DRC and RoC to support official public health initiatives.

What is the timeline for implementing these models?

The project period runs from 2024-10-01 to 2026-09-30, indicating that the final models and data will be fully available by September 2026.

Consortium

Who built it

The consortium consists of 5 partners across 4 countries (CD, CG, ES, IT). It is heavily weighted toward non-commercial entities, with 1 university, 2 research organizations, and 2 other organizations. There are 0 industry partners and 0 SMEs, indicating the project is currently driven by academic and public health goals rather than immediate commercialization.

How to reach the team

Contact R-EVOLUTION WORLDWIDE SRL - IMPRESA SOCIALE in Italy

Next steps

Talk to the team behind this work.

Contact us to bridge the gap between this research and your diagnostic product pipeline.

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