SciTransfer
MoSS · Project

Low-Cost DNA Data Storage for Massive Long-Term Archiving

digitalTestedTRL 6

Imagine storing all the world's digital files inside tiny biological molecules instead of giant server farms. This project uses enzymes—nature's own tools—to write data into DNA, making it much cheaper than current lab methods. It's like switching from an expensive hand-written ledger to a high-speed digital printer for biological storage.

By the numbers
0.001
cost per nucleotide in current synthetic DNA (USD)
7
orders of magnitude cost difference between DNA storage and tape
The business problem

What needed solving

Digital archiving is currently limited by the high cost and energy requirements of magnetic tape and disks. Synthetic DNA offers extreme density but is currently too expensive for mass adoption due to the cost of chemical synthesis.

The solution

What was built

An automated DNA synthesis and sequencing platform including enzyme kits, workstation modules, and a two-layer encoding model for different data types.

Audience

Who needs this

Cloud storage providersNational archivesBig Data analytics firmsSynthetic biology companies
Business applications

Who can put this to work

Cloud Computing
enterprise
Target: Cold-storage data center provider

If you are a data center provider dealing with the massive energy costs of magnetic tape archives — this project developed an enzymatic DNA synthesis system that aims to reduce the cost of writing data by several orders of magnitude. This allows for denser, more permanent archival storage.

Government & Public Records
enterprise
Target: National digital archive agency

If you are a government agency dealing with the decay of digital media over decades — this project developed a molecular storage system that provides a stable, long-term medium. It uses automated sequencing and synthesis to ensure data remains retrievable.

Biotechnology
SME
Target: Synthetic biology lab

If you are a biotech firm dealing with the high cost of $0.001 per nucleotide for synthetic DNA — this project developed enzymatic synthesis kits and automation modules. This lowers the barrier for creating large-scale synthetic DNA libraries.

Frequently asked

Quick answers

How does the cost compare to current methods?

Current synthetic DNA costs $0.001 per nucleotide, which is seven orders of magnitude more expensive than tape. MoSS aims to dramatically reduce this cost by using enzymatic synthesis instead of phosphonamidite chemistry.

Can this be scaled for industrial use?

Yes, the project focused on moving from TRL4 to TRL6, developing a scalable encoding model and automated workstation modules to handle massive amounts of content.

What is the IP or licensing status?

Based on available project data, the technology is being developed by Helixworks Technologies Limited in collaboration with academic partners, with a focus on building a commercial business case for EIC Accelerator readiness.

How is the data retrieved?

The system includes a sequencing preparation kit and a device for automating library preparation, supported by a read consensus solution developed by EURECOM.

What is the project timeline?

The project ran from 2022-05-01 to 2024-04-30.

Consortium

Who built it

The consortium is a lean, 3-partner group combining industrial agility with academic depth. With a 33% industry ratio (Helixworks as the SME coordinator), the project balances commercial drive with high-level research from Imperial College London and EURECOM, ensuring the technology is both scientifically sound and market-oriented.

How to reach the team

Contact Helixworks Technologies Limited in Ireland for commercial licensing and TRL6 prototype details.

Next steps

Talk to the team behind this work.

Contact us to explore integration of enzymatic DNA storage into your archival strategy.