SciTransfer
LIAC FLASH · Project

High-Precision Intraoperative Radiation System for Safer and More Effective Cancer Tumor Removal

healthMarket-readyTRL 8

Imagine trying to remove a weed from a garden without harming the delicate flowers surrounding it. This technology acts like a super-fast laser that kills the weed instantly before the surrounding flowers even realize what happened. It allows surgeons to deliver powerful radiation directly to a tumor during surgery while protecting healthy organs.

By the numbers
19.3m
new cancer cases (2020)
10m
cancer deaths (2020)
2/3
cancer patients treated with radiation therapy
The business problem

What needed solving

Traditional radiation therapy is often limited by the risk of damaging healthy organs surrounding a tumor. This prevents doctors from using the high doses necessary to successfully treat certain cancers, reducing patient survival rates.

The solution

What was built

A medical linear accelerator (LINAC) for intraoperative use that delivers both conventional and FLASH dose-rate radiotherapy, including an AI-powered imaging and planning unit.

Audience

Who needs this

Surgical oncology departmentsMedical linear accelerator manufacturersSpecialized cancer treatment centersRobotic surgery equipment developers
Business applications

Who can put this to work

Medical Device Manufacturing
enterprise
Target: Surgical Equipment Provider

If you are a surgical equipment provider dealing with the limitations of traditional radiation tools — this project developed a medical linear accelerator that delivers FLASH dose-rates to widen the therapeutic window. This allows for higher doses to tumors while keeping side effects low.

Healthcare Services
mid-size
Target: Private Oncology Clinic

If you are a private oncology clinic dealing with tumors that cannot be treated due to their location near critical organs — this project developed an IOeRT system with 5 degrees of freedom. This ensures easier access to the anatomical region of interest in standard operating rooms.

Health Tech Software
SME
Target: AI Medical Imaging Firm

If you are an AI medical imaging firm dealing with the need for precise treatment planning — this project developed an imaging and planning unit using artificial intelligent software. This simplifies the docking process of the accelerator through image guidance.

Frequently asked

Quick answers

What is the cost or price of the LIACFLASH system?

Based on available project data, specific pricing and cost details are not provided.

Is the technology ready for industrial scale production?

The project reached TRL8 by May 2025, indicating the system is developed and validated in its final form, which is a prerequisite for industrial scaling.

What is the IP or licensing status of the FLASH effect implementation?

Based on available project data, the system is built on the scientific discovery of the FLASH effect, but specific patent or licensing terms are not listed.

How does the system integrate into existing hospital workflows?

The system is designed to be easy to handle in standard operating rooms and uses image guidance to simplify the docking process.

What is the timeline for market availability?

The project period concluded on 2025-05-31, with the system reaching TRL8 by that date.

Consortium

Who built it

The project is led by a single Italian SME, S.I.T. - SORDINA IORT TECHNOLOGIES SPA. With a 100% industry ratio and a single partner, the project demonstrates a highly streamlined execution focused on commercialization rather than academic research, moving rapidly from design to TRL8.

How to reach the team

Contact S.I.T. - SORDINA IORT TECHNOLOGIES SPA in Italy

Next steps

Talk to the team behind this work.

Contact us to explore licensing or partnership opportunities for this TRL8 oncology technology.

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