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IMPRIMA · Project

Scaling Child-Friendly Malaria Transmission Blocking Drugs in African Markets

healthPilotedTRL 7

Imagine a medicine that doesn't just cure a sick person, but also stops them from passing the disease to others. This project is testing a tasty, kid-friendly version of a drug called primaquine to make it easier for children to take. By doing this, they hope to break the chain of malaria transmission across three different African countries.

By the numbers
249 million
estimated clinical malaria cases in 2023
608,000
estimated deaths from malaria in 2023
3
African nations for implementation study
7
participating partners
The business problem

What needed solving

Low uptake of malaria transmission-blocking drugs due to a lack of child-friendly versions and safety fears regarding G6PD deficiency. This prevents the interruption of the malaria cycle in pediatric populations.

The solution

What was built

A real-life implementation study and a flavoured paediatric primaquine formulation designed for children.

Audience

Who needs this

Generic pharmaceutical manufacturersGlobal health NGOsAfrican national health ministriesPediatric drug formulation specialists
Business applications

Who can put this to work

Pharmaceuticals
enterprise
Target: Generic drug manufacturer

If you are a drug manufacturer dealing with low adoption of adult-only malaria pills — this project developed a flavoured paediatric formulation that improves patient acceptability. This allows for the expansion of the target market to include children.

Healthcare Logistics
mid-size
Target: Medical supply distributor

If you are a distributor dealing with the need for specialized antimalarial portfolios in Africa — this project provides real-life implementation data across 3 countries. This evidence helps in planning the rollout of transmission-blocking therapies.

Public Health Consulting
SME
Target: Health policy advisory firm

If you are a consultancy dealing with outdated drug policies in malaria-endemic regions — this project generates clinical and sociological evidence to shift policy toward single low dose primaquine. This creates a roadmap for national health system updates.

Frequently asked

Quick answers

What is the cost or price of the new formulation?

Based on available project data, the specific cost or price of the flavoured primaquine is not mentioned.

Can this be produced at an industrial scale?

The project builds on the 'Developing Paediatric Primaquine' project which aimed to prequalify formulations, suggesting a move toward industrial standards, though specific scale-up metrics are not provided.

Who owns the IP or licensing for the flavoured drug?

Based on available project data, the IP and licensing details are not specified, though the project involves a consortium of 7 partners including the University of Strasbourg.

What is the timeline for market entry?

The project runs from 2023-04-01 to 2027-03-31, focusing on implementation studies and policy shifts during this window.

How is the drug integrated into existing treatments?

It is designed as a single low dose primaquine (SLDPQ) to be added to existing artemisinin-based combination therapies (ACTs).

Consortium

Who built it

The consortium is heavily academic, with 5 universities and 1 other organization, representing 86% of the partners. However, there is a strategic 14% industry presence (1 company), which is critical for translating the clinical findings into a commercial product. The geographic spread across 6 countries (including BF, BI, MG) ensures the results are validated across diverse epidemiological profiles.

How to reach the team

Contact the University of Strasbourg regarding the implementation of paediatric primaquine.

Next steps

Talk to the team behind this work.

Contact us to identify the industrial partner involved in the IMPRIMA consortium for licensing opportunities.

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