If you are an IVF clinic dealing with low pregnancy success rates — this project developed a non-invasive screening tool that selects the most viable embryos based on their metabolism. This helps improve the success rate of IVF for the one in six couples globally facing infertility.
Non-Invasive Single-Cell Metabolic Analysis Tool for IVF and Drug Screening
Imagine trying to see if a tiny seed is healthy without cracking it open. This technology acts like a super-powered magnifying glass that reads the chemical energy of a single cell without touching or harming it. It combines a signal booster and a tiny sensor to see exactly how a cell is functioning in real-time.
What needed solving
Current metabolic analysis methods cannot provide reliable data at the micro to picolitre scale without disrupting the cell. This creates a gap in IVF embryo selection and preclinical drug response monitoring.
What was built
A benchtop tool combining a hyperpolarization platform and a micro-NMR sensor capable of analyzing volumes down to 1 nL.
Who needs this
Who can put this to work
If you are a biotech company dealing with slow preclinical drug testing — this project developed a metabolic assessment tool that monitors how individual cells respond to treatment. This optimizes the screening of drug candidates before moving to expensive trials.
If you are a diagnostic lab dealing with the inability to get reliable metabolic data at the picolitre scale — this project developed a benchtop micro-NMR device. It allows for the discovery of hidden disease mechanisms by profiling individual cells.
Quick answers
What is the cost of implementing this technology?
Based on available project data, the specific commercial price or implementation cost is not mentioned, though the project received an EU contribution of EUR 1,998,750 for development.
Can this be scaled for industrial use?
The project is developing a benchtop tool designed for integration into standard NMR systems, suggesting a path toward laboratory and clinical scale adoption.
Who owns the IP and how is licensing handled?
Based on available project data, the technology is developed by a consortium of two SMEs, NVision Quantum Technologies and Annaida; specific licensing terms are not provided.
How long does the integration take?
The project period runs from 2024-04-01 to 2026-09-30, indicating the timeline for optimization and validation of the integrated system.
How does it integrate with existing lab equipment?
The sensor head was specifically redesigned for successful integration into standard benchtop NMR systems with an easy sample loading mechanism.
Who built it
The consortium is highly streamlined and commercially focused, consisting of 2 SMEs from Germany and Switzerland. With a 100% industry ratio, the project bypasses academic delays and focuses directly on the integration of two proprietary technologies: NVision's hyperpolarization platform and Annaida's micro-NMR sensors.
Contact NVision Quantum Technologies GmbH in Germany
Talk to the team behind this work.
Contact us to explore licensing opportunities for micro-NMR metabolic sensing.