SciTransfer
GenPath Africa · Project

Genomic Surveillance System for Tracking Drug-Resistant Infections in Africa

healthTestedTRL 5

Imagine having a high-tech security camera system, but for germs. Instead of filming people, it reads the genetic code of viruses and bacteria to see how they are changing and which medicines they can ignore. By checking things like wastewater, it acts as an early warning system to stop outbreaks before they spread.

By the numbers
5
partners in consortium
5
countries involved
18
months of initial milestone achievement
The business problem

What needed solving

Traditional disease monitoring is too slow to catch drug-resistant mutations in HIV and TB, leading to ineffective treatments and uncontrolled outbreaks in southern and eastern Africa.

The solution

What was built

A genomic surveillance network including a low-cost Oxford Nanopore drug resistance test and wastewater monitoring protocols for emerging pathogens.

Audience

Who needs this

IVD (In-Vitro Diagnostics) companiesAnti-infective pharmaceutical firmsPublic health monitoring agenciesBiotech firms specializing in NGS (Next Generation Sequencing)
Business applications

Who can put this to work

Diagnostics
SME
Target: Medical device manufacturer

If you are a medical device manufacturer dealing with slow diagnostic turnaround for TB and HIV — this project developed a low-cost Oxford Nanopore drug resistance test that provides faster, genetic-based results.

Pharmaceuticals
enterprise
Target: Drug development firm

If you are a drug development firm dealing with the emergence of drug-resistant strains — this project developed genomic epidemiology data platforms that identify which medicines are failing in real-time.

Public Health Infrastructure
mid-size
Target: Environmental monitoring service

If you are an environmental monitoring service dealing with undetected urban outbreaks — this project developed wastewater surveillance methods to detect emerging pathogens without needing individual patient samples.

Frequently asked

Quick answers

What is the cost or price of the developed tests?

Based on available project data, specific pricing is not listed, but the project has validated a 'low-cost' Oxford Nanopore drug resistance test.

Is this system ready for industrial scale?

The project is currently in the pilot and capacity-building phase, focusing on transferring technology to national institutes in Mozambique and South Africa.

What are the IP and licensing terms for the genomic platforms?

Based on available project data, there is no mention of specific licensing terms; however, the goal is to make data available in public databases.

How does this integrate with existing health systems?

It integrates by connecting specialized genomics facilities with national public health institutes to translate scientific data into public health actions.

What is the timeline for deployment?

The project period runs from 2023-05-01 to 2027-04-30, with initial milestones achieved in the first 18 months.

Consortium

Who built it

The consortium is lean and highly specialized, consisting of 5 partners across 5 countries. It features a 20% industry ratio with 1 SME, balanced by 2 universities and 2 research organizations. This structure suggests a strong focus on technology transfer from academic research to public health implementation in Africa.

How to reach the team

Contact Stellenbosch University regarding the Genomic Epidemiology Network in Sub-Saharan Africa.

Next steps

Talk to the team behind this work.

Contact us to explore licensing opportunities for the low-cost Nanopore drug resistance tests.

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