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FASS · Project

High-Speed Optical Instrument for Sustainable and Low-Cost Drug Solubility Testing

healthTestedTRL 5

Imagine trying to find out how much sugar dissolves in a cup of tea, but you have to do it for thousands of different chemicals. Usually, this is either a fast guess or a slow, expensive process that wastes a lot of material. This technology uses special laser light to get the exact answer almost instantly while using tiny amounts of chemicals.

By the numbers
90%
reduction in testing time and costs
99%
reduction in chemical consumption
97%
reduction in electricity use
80%
reduction in compounds required
The business problem

What needed solving

Current solubility testing is a bottleneck in drug discovery because it is either fast but inaccurate, or accurate but slow and wasteful of expensive chemicals.

The solution

What was built

A prototype solubility measurement instrument based on high-efficiency second harmonic scattering (SHS) and a benchmarking system against HPLC.

Audience

Who needs this

Pharmaceutical R&D labsBiotech startupsCDMOsChemical synthesis companies
Business applications

Who can put this to work

Pharmaceuticals
enterprise
Target: Drug Discovery Firm

If you are a drug discovery firm dealing with slow early-stage screening and high material waste — this project developed an optical measurement instrument that reduces testing time and costs by 90% and chemical consumption by 99%.

Contract Manufacturing
mid-size
Target: CDMO (Contract Development and Manufacturing Organization)

If you are a CDMO dealing with resource-intensive formulation chemistry — this project developed a non-destructive solubility tool that cuts electricity use by 97% and requires 80% fewer compounds.

Chemical Synthesis
SME
Target: Specialty Chemical Producer

If you are a chemical producer dealing with the high cost of standard solubility tests — this project developed a high-efficiency scattering system that reduces measurement costs by 90%.

Frequently asked

Quick answers

How does this impact the cost of solubility testing?

The technology is designed to reduce testing costs by 90% compared to current gold-standard methods.

Can this be scaled for industrial use?

Yes, the project aims to develop a robust demonstrator instrument and a go-to-market strategy via a dedicated startup for industrial deployment.

Who owns the IP and how is it licensed?

Based on available project data, a dedicated startup is leading the commercialization and development of the business model.

Does this comply with environmental regulations?

Yes, it contributes to the European Green Deal by reducing chemical consumption by 99% and energy use by 97%.

What is the timeline for availability?

The project period runs from June 1, 2024, to November 30, 2026, focusing on developing a demonstrator and validating it with early adopters.

Consortium

Who built it

The consortium is strategically balanced for commercialization, featuring a 25% industry ratio with 2 SMEs and 1 industry partner. It combines the commercial drive of a startup with the technical validation of a European research infrastructure (EU-OPENSCREEN ERIC), a technology center, and a pharmaceutical research institute, ensuring the product is tested against real-world pharma needs.

How to reach the team

Contact EU-OPENSCREEN ERIC in Germany

Next steps

Talk to the team behind this work.

Contact us to connect with the FASS startup for early adopter validation.

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