Imagine making medicine like a chef who finds a way to use fewer toxic cleaners and recycle every drop of oil in the kitchen. Instead of throwing away chemical waste, this project uses smart filters and natural sponges to catch harmful impurities. It also uses a digital twin—like a flight simulator for a factory—to make the process cleaner and faster.
Pharmaceutical companies face high costs and regulatory pressure due to toxic solvent waste and carcinogenic impurities in their production lines. Traditional batch processing is often inefficient and environmentally damaging.
A set of green manufacturing tools including continuous synthesis routes, membrane-based solvent recovery systems, and a Digital Twin platform for process control.
If you are an API producer dealing with high solvent waste—this project developed continuous manufacturing and green solvent routes that reduce solvent use by 20–40%. This lowers raw material costs and waste disposal fees.
If you are a recovery specialist dealing with carcinogenic impurities in recycled chemicals—this project developed membrane technologies that increased recycled isobutyl by 15–25%, and up to 90% in specific cases.
If you are a manufacturer dealing with inefficient batch processing for tablets—this project developed Hot Melt Extrusion (HME) for immediate and modified release formulations to improve production speed and quality.
Based on available project data, specific pricing is not provided, but the project achieves a 20–40% reduction in solvent use, which typically lowers operational expenditure.
Yes, the innovations were scaled up in 6 industrial pilots at pharmaceutical sites to validate green chemistry and continuous process innovations.
Based on available project data, there is no specific mention of licensing terms, though the project involves a co-creation lab between industry and research partners.
Yes, the project focuses on compliant-by-design methods and assesses environmental risks of APIs and by-products to provide guidance for regulators.
The project uses a digital workflow and a Digital Twin for process optimization and dynamic control to guide the scale-up from TRL3-4 to TRL5-6.
The consortium is highly industry-centric with a 50% industry ratio, comprising 8 industrial partners and 7 SMEs. With 16 partners across 7 countries, the group balances academic research (3 universities, 3 research centers) with practical application, ensuring that the 6 industrial pilots are grounded in commercial reality.
Contact AIMPLAS in Spain for details on the co-creation lab and pilot results.
Contact us to find the specific green solvent or membrane technology suitable for your API production line.
