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EnterBio · Project

Gut-Based Bioelectronic Interface for Non-Invasive Brain Disorder Treatment

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Imagine your gut is like a second brain that talks to your head. Instead of performing risky brain surgery to treat diseases, this project creates tiny, flexible electronic patches for the gut. These patches act like a remote control, sending signals through the gut to fix brain issues without ever touching the skull.

By the numbers
7
consortium partners
29%
industry ratio
The business problem

What needed solving

Treating neurological disorders currently requires highly invasive brain surgery. There is a critical lack of tools to modulate brain function through the more accessible enteric nervous system.

The solution

What was built

Flexible thin-film organic electrode arrays for colon implantation and iontronic devices for localized neurotransmitter delivery.

Audience

Who needs this

Neuromodulation device manufacturersNeuro-pharmaceutical companiesGastroenterology medical tech firmsBrain-computer interface (BCI) developers
Business applications

Who can put this to work

Medical Devices
enterprise
Target: Neuromodulation device manufacturer

If you are a device manufacturer dealing with the high risks of invasive brain implants — this project developed flexible, implantable organic electronics that allow for brain modulation via the gut. This provides a less invasive alternative for treating CNS disorders.

Pharmaceuticals
enterprise
Target: Drug delivery system developer

If you are a pharma company dealing with imprecise drug targeting for neurological conditions — this project developed iontronic devices for highly localized, fluid-free delivery of neurotransmitters. This allows for precise chemical stimulation of the enteric nervous system.

Biotechnology
SME
Target: Neuro-diagnostic startup

If you are a biotech firm dealing with the lack of tools to monitor the gut-brain axis — this project developed high-resolution sensing signals in vivo. This enables the prediction and control of brain dysfunction through gut activity.

Frequently asked

Quick answers

What is the estimated cost or price of the devices?

Based on available project data, there is no specific pricing or unit cost mentioned; the project is currently in the research and development phase.

Can this technology be produced at an industrial scale?

The project uses thin-film organic electrode arrays and graphene bioelectronics, but based on available project data, industrial scaling metrics have not yet been established.

What is the IP and licensing status for these bioelectronic tools?

Based on available project data, specific patent numbers or licensing terms are not listed, though the project involves 7 partners including 2 industry entities.

What is the timeline for clinical application?

The project period runs from 2024-03-01 to 2028-02-29, suggesting that clinical readiness will be evaluated toward the end of this window.

How is the device integrated into the patient's body?

The devices are designed as flexible, implantable tools for the colon to target the enteric nervous system, avoiding the need for brain-invasive surgery.

Consortium

Who built it

The consortium is a balanced mix of 7 partners across 4 countries, featuring a 29% industry ratio. With 3 universities and 2 research institutions, the project is heavily weighted toward fundamental discovery, but the inclusion of 2 industry partners and 1 SME suggests a clear intent to translate these bioelectronic tools into commercial medical products.

How to reach the team

Contact Linkopings Universitet regarding the EnterBio project

Next steps

Talk to the team behind this work.

Contact us to explore licensing opportunities for gut-brain bioelectronics.

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