If you are a drug developer dealing with the high cost of late-stage failures — this project developed an adaptive platform trial that tests 4 candidate treatments in primary care. This allows you to identify safety and efficacy early in the disease trajectory before moving to expensive larger phases.
European Primary Care Clinical Trial Network for Rapid Antiviral Treatment Testing
Imagine a fast-track testing system for medicines that works in your local doctor's office instead of just big hospitals. It allows researchers to quickly swap in and out different treatments for flu-like illnesses to see what works best. This means people can get effective medicine earlier at home, preventing them from needing a hospital bed.
What needed solving
Lack of evidence-based treatments for respiratory viruses in primary care leads to higher hospital admission rates and unsustainable health service loads during pandemics.
What was built
An adaptive platform trial (APT) infrastructure across 8 countries to test the safety and efficacy of antiviral treatments in community settings.
Who needs this
Who can put this to work
If you are a diagnostics company dealing with low adoption of rapid tests — this project developed a workflow where rapid point-of-care tests are used for patient inclusion. This integrates your hardware directly into the clinical trial process for virus-specific agents.
If you are a clinic operator dealing with unsustainable patient loads during epidemics — this project developed a primary care research network. This enables your facilities to provide evidence-based therapeutics that reduce the need for hospital admissions.
Quick answers
What is the cost of accessing this platform?
Based on available project data, there is no specific pricing or cost mentioned for the use of the platform.
Can this be scaled to other respiratory viruses?
Yes, the project is designed for COVID-19 and COVID-like illnesses, specifically mentioning influenza and respiratory syncytial virus.
Who owns the IP or licensing for the candidate treatments?
Based on available project data, the IP and licensing terms for the 4 candidate treatments are not specified.
How long does the trial infrastructure take to set up?
The project period runs from 2021-12-01 to 2026-11-30, with the first phase focusing on organizational, legal, and ethical setup.
How does this integrate with existing hospital trials?
It completes the Ecraid vision by adding primary care trials to the existing suite of intensive care and hospital ward trials.
Who built it
The consortium consists of 6 partners from 5 countries (BE, FR, NL, NO, UK). It is heavily weighted toward non-industrial actors, with 3 universities and 2 research organizations, and only 1 SME. There are 0 traditional industry partners, indicating the project is currently driven by academic and public health research rather than commercial interests.
Contact STICHTING EUROPEAN CLINICAL RESEARCH ALLIANCE ON INFECTIOUS DISEASES in the Netherlands
Talk to the team behind this work.
Contact us to identify potential antiviral candidates for the ECRAID-Prime platform.