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eBRAIN-Health · Project

Privacy-Compliant Digital Twin Platform for Brain Disease Modeling and Simulation

healthTestedTRL 5

Imagine having a digital copy of a person's brain that doctors can use to test treatments without any risk to the patient. This system creates these 'virtual brains' using a mix of medical scans and genetic data while keeping the person's identity completely secret. It is like a flight simulator, but for neurology, helping researchers predict how dementia progresses.

By the numbers
thousands
multilevel virtual brains
22
consortium partners
The business problem

What needed solving

Biomedical research is stalled because patient data cannot be shared or used for personalized therapy without risking the patient's identity. Current anonymization methods are insufficient for complex neuroimaging data.

The solution

What was built

A distributed research platform and four demonstrators: a neurodegeneration simulation tool, a multiscale model visualizer, a disease prediction improver, and a subclass identification tool.

Audience

Who needs this

Pharmaceutical R&D departmentsNeurology clinicsMedical AI startupsHealth data management companies
Business applications

Who can put this to work

Pharmaceuticals
enterprise
Target: Drug Discovery Firm

If you are a drug discovery firm dealing with high failure rates in clinical trials — this project developed a simulation demonstrator for neurodegeneration that allows testing drug effects on virtual brain twins before human trials.

Health Tech
SME
Target: Medical AI Software Developer

If you are a medical AI software developer dealing with strict GDPR rules on patient data — this project developed a distributed research platform that ensures data protection by design and by default.

Diagnostics
mid-size
Target: Neurological Diagnostic Center

If you are a neurological diagnostic center dealing with late-stage dementia detection — this project developed a demonstrator improving disease prediction to identify risks earlier using multiscale data.

Frequently asked

Quick answers

What is the cost or pricing model for using the platform?

Based on available project data, no specific pricing or commercial cost model is mentioned; it is described as a research infrastructure for academia and the private sector.

Can this be scaled to an industrial level?

The project aims to provide thousands of multilevel virtual brains, suggesting a high capacity for scaling across large patient cohorts.

What are the IP and licensing terms for the demonstrators?

Based on available project data, specific licensing terms are not provided, though it is designed as an open yet protected space for innovation.

How does the system handle GDPR and data privacy regulations?

The platform is built to be compliant with EU General Data Protection Regulations (GDPR) using data protection by design and by default to prevent re-identification.

How is the platform integrated with existing medical data?

It integrates data from multiple sources, including genomics, proteomics, imaging, and wearables, annotating them to a common 3D brain space.

Consortium

Who built it

The consortium is heavily weighted toward research and academia, with 12 universities and 8 research institutes. However, there is a strategic industrial presence with 2 industry partners and 4 SMEs, representing a 9% industry ratio, which indicates a bridge between theoretical brain modeling and commercial health-tech application.

How to reach the team

Contact Charité - Universitätsmedizin Berlin

Next steps

Talk to the team behind this work.

Contact us to explore licensing opportunities for the virtual brain demonstrators.

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