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DURA-store · Project

Ultra-Stable Biological Data Storage for Long-Term Digital Archiving

digitalPrototypeTRL 3

Imagine a hard drive made of biological molecules instead of silicon. Instead of using electricity and heat, it uses enzymes to write and read data at room temperature. It even uses proteins from nature's toughest organisms to keep the information from decaying over time.

By the numbers
37°C
Maximum operational temperature for isothermal reactions
The business problem

What needed solving

Digital data is growing faster than current storage hardware can sustainably handle. Existing DNA storage is mostly 'cold storage,' meaning it is too slow and static for practical, real-time data access.

The solution

What was built

A Solid Phase Molecular Drive (SPMD) using polystyrene beads and a specific strand architecture for isothermal data writing, reading, and deleting.

Audience

Who needs this

Cloud archive providersSynthetic biology companiesGovernmental long-term record keepersDeep-archive data management firms
Business applications

Who can put this to work

Cloud Computing & Data Centers
enterprise
Target: Cold-storage archive provider

If you are a data center provider dealing with the massive energy costs of maintaining legacy archives — this project developed a solid-state biological storage device that operates at 37°C. This reduces the need for expensive temperature cycling and lowers long-term maintenance costs.

Biotechnology
mid-size
Target: Synthetic biology lab

If you are a biotech firm dealing with static genetic libraries that cannot be easily updated — this project developed an in vivo storage solution using bacteriophages. This allows for dynamic data operations and random access to information stored directly inside bacteria.

Cybersecurity
enterprise
Target: High-security government archive

If you are a security agency dealing with the risk of digital data degradation over decades — this project developed a stabilization strategy using extremophile-derived molecules. This ensures the long-term stability of stored information in both lab and living environments.

Frequently asked

Quick answers

How does this reduce operational costs compared to current DNA storage?

The system uses isothermal reactions that do not exceed 37°C, eliminating the need for costly and energy-intensive temperature cycling.

Can this technology be scaled for industrial use?

Based on available project data, the project has established a polystyrene-based solid-phase support, but industrial-scale manufacturing metrics are not yet provided.

What is the IP or licensing status of the Solid Phase Molecular Drive (SPMD)?

Based on available project data, the project has created a new strand design and refined the SPMD, but specific patent or licensing terms are not listed.

How is the data accessed and modified?

Data is managed through enzymatic reactions and nucleic acid strands, allowing for specific write, delete, and read operations via unique Data ID sequences.

What is the timeline for a commercial version?

The project period runs from 2023-10-01 to 2028-09-30, suggesting the technology is currently in the development and proof-of-concept phase.

Consortium

Who built it

The project is led by a single academic partner, Karolinska Institutet in Sweden. With 0% industry participation and a total of 1 partner, the project is currently driven by fundamental research rather than commercial partnerships, indicating a high-risk, high-reward early-stage development profile.

How to reach the team

Contact the research office at Karolinska Institutet regarding the DURA-store project.

Next steps

Talk to the team behind this work.

Contact SciTransfer to identify industrial partners for scaling this biological storage prototype.