SciTransfer
deCYPher · Project

AI-Driven Microbial Production of High-Value Plant Compounds for Industrial Use

manufacturingTestedTRL 5

Imagine trying to brew a rare plant scent in a lab, but the biological 'machinery' needed is too complex to build. This project uses AI as a master blueprint to teach microbes how to build these complex plant molecules. It's like giving a bacteria a digital instruction manual to perfectly recreate nature's most valuable chemicals.

By the numbers
11
consortium partners
36%
industry ratio
5
target TRL
The business problem

What needed solving

High-value oxygenated plant metabolites are currently difficult to produce because the necessary enzymes are hard to engineer in microbes. This makes these compounds expensive and inaccessible for wide industrial use.

The solution

What was built

A standardized AI/ML pipeline for the Design-Build-Test-Learn cycle and smart databases to optimize the production of flavonoids and terpenoids.

Audience

Who needs this

Fragrance housesNutraceutical manufacturersSynthetic biology startupsSpecialty chemical producers
Business applications

Who can put this to work

Fragrances & Flavors
any
Target: Scent and taste ingredient manufacturer

If you are a scent manufacturer dealing with the high cost of extracting rare plant oils — this project developed an AI/ML pipeline that enables the microbial production of terpenoids. This allows for a more stable and sustainable supply of fragrance molecules.

Nutraceuticals
mid-size
Target: Phytonutrient supplement producer

If you are a supplement producer dealing with inconsistent raw material quality from crops — this project developed a way to produce flavonoids using microbes. This ensures a pure, scalable, and consistent source of health-promoting plant metabolites.

Biotechnology
SME
Target: Synthetic biology service provider

If you are a biotech firm dealing with the difficulty of engineering cytochrome P450 enzymes — this project developed a standardized AI/ML platform for the Design-Build-Test-Learn cycle. This reduces the trial-and-error time when creating oxygenated plant metabolites.

Frequently asked

Quick answers

What is the cost or price of the technology?

Based on available project data, specific pricing or cost figures are not provided; however, the project aims to make production more cost-effective than traditional chemical synthesis.

Can this be produced at an industrial scale?

The project aims to move from TRL 2-3 to TRL 5, focusing on scalable and competitive production of oxygenated plant metabolites to support economic valorization.

How is the IP and licensing handled?

Based on available project data, specific licensing terms are not mentioned, but the project involves 11 partners including 3 SMEs and 4 industry entities.

What regulations affect this technology?

The project actively involves regulators to reflect on the societal and ethical implications of combining AI and synthetic biology.

How long does the development timeline take?

The project period is from 2023-09-01 to 2027-08-31.

How is this integrated into existing workflows?

It integrates into the biotech value chain via a modular AI/ML pipeline that covers every step of the Design-Build-Test-Learn cycle.

Consortium

Who built it

The consortium is well-balanced for commercialization, featuring 11 partners across 7 countries. With a 36% industry ratio, including 3 SMEs and 4 industrial partners, there is a strong bridge between the 2 universities and 4 research organizations to ensure the AI/ML tools are practically applicable to the biotech value chain.

How to reach the team

Contact Universiteit Gent

Next steps

Talk to the team behind this work.

Contact us to connect with the deCYPher consortium for AI-driven bioproduction licensing.

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