If you are a medical device company dealing with the need for more functional imaging capabilities — this project developed a deuterium MRI acquisition scheme that enables PET-like images on 3T scanners. This allows your hardware to perform cancer detection without requiring significant hardware changes.
Radiation-Free Cancer Imaging Using Deuterium-Enhanced MRI Technology
Imagine if you could get the detailed 'sugar-mapping' of a cancer scan without the radiation risks of a PET scan. This technology uses a special version of sugar tagged with heavy hydrogen (deuterium) that acts like a beacon for MRI machines. It allows doctors to see where tumors are hiding using standard MRI equipment, making it safe for children and pregnant women.
What needed solving
Current cancer staging via FDG-PET is limited by ionizing radiation, restricting the number of scans per year and preventing use in children and pregnant women.
What was built
A deuterated-2-deoxy-D-glucose (DDG) contrast agent and the corresponding MRI acquisition software/hardware for 3T scanners.
Who needs this
Who can put this to work
If you are a chemical manufacturer dealing with the demand for safer diagnostic tracers — this project developed a deuterated-2-deoxy-D-glucose (DDG) agent. This stable isotope chemistry provides a non-ionizing alternative to FDG-PET for tumor staging and monitoring.
If you are a clinic dealing with the limitation of only 2-3 PET scans per year per patient due to radiation — this project developed a DDG-MRI technique. This allows for more frequent treatment monitoring and expands your patient base to include children and pregnant women.
Quick answers
What is the expected cost of this procedure compared to current methods?
Based on available project data, the DDG-MRI technology is expected to cost the same as a PET scan.
Can this be scaled to existing hospital infrastructure?
Yes, the technology is designed for clinical MRI 3T scanners and does not require significant hardware changes or alterations to the MRI suite workflow.
What is the IP and licensing strategy for the contrast agent?
The project includes a specific objective to develop a strategy for the commercialization of the DDG contrast agent and the associated MRI technology.
Are there regulatory hurdles for the new imaging agent?
The project is actively studying the human regulatory aspects of DDG to ensure it can be used safely in clinical settings.
How long does the imaging process take?
The expected scan time for the DDG-MRI technique is about 2 minutes.
Who built it
The consortium shows a strong commercial orientation with a 43% industry ratio, consisting of 3 industrial partners and 4 universities across 6 countries. The presence of SMEs and large medical organizations like Hadassah suggests a balanced pipeline from academic research to industrial application.
Contact Hadassah Medical Organization in Israel
Talk to the team behind this work.
Contact us to explore licensing opportunities for the DDG contrast agent.