SciTransfer
COMBINE-CT · Project

AI-Powered CT Workflow to Reduce Unnecessary Heart Procedures and Improve Hospital Efficiency

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Imagine using a high-tech 3D map of your heart to decide exactly where a surgeon needs to work, rather than guessing and exploring during surgery. This project creates a smart system that reads CT scans automatically to find blockages with high precision. It acts like a digital gatekeeper, ensuring only patients who truly need an invasive procedure get one.

By the numbers
60%
CAD patients unnecessarily undergoing ICA
200 million
Individuals affected by CAD globally in 2019
9 million
Annual deaths from CAD globally
973,000
CAD-related deaths in the EU in 2019
The business problem

What needed solving

60% of coronary artery disease patients undergo invasive angiography unnecessarily due to low diagnostic sensitivity. This creates massive hospital inefficiency and exposes patients to avoidable risks.

The solution

What was built

A vendor-agnostic, AI-powered CCTA workflow including automated stenosis algorithms and a standardized scan protocol for chronic CAD patients.

Audience

Who needs this

Medical imaging device manufacturersAI healthcare software developersHospital network administratorsInterventional cardiology clinics
Business applications

Who can put this to work

Medical Imaging
enterprise
Target: CT Scanner Manufacturer

If you are a scanner manufacturer dealing with low software differentiation — this project developed AI-powered CCTA algorithms that enable definitive ischemia diagnosis. This allows your hardware to provide a complete end-to-end clinical workflow for chronic CAD patients.

Digital Health
mid-size
Target: AI Diagnostic Software Provider

If you are a software provider dealing with the need for vendor-agnostic tools — this project developed automated stenosis algorithms for coronary analysis. This allows your software to integrate into various hospital environments regardless of the scanner brand.

Healthcare Management
enterprise
Target: Private Hospital Group

If you are a hospital group dealing with the fact that 60% of CAD patients unnecessarily undergo an ICA — this project developed a CCTA-enabled workflow. This reduces wasted Cath lab time and improves overall hospital efficiency.

Frequently asked

Quick answers

What is the cost or pricing model for this technology?

Based on available project data, no specific pricing or cost-per-unit information is provided.

Is this technology ready for industrial scale?

The project is developing a vendor-agnostic workflow and conducting five multicentre clinical trials to ensure the tools are scalable across different hospital sites.

Who owns the IP and how is licensing handled?

Based on available project data, the coordinator is Philips Medical Systems, but specific licensing terms are not detailed in the report.

How does this integrate into existing hospital workflows?

The project focuses on closing gaps in the CAD workflow by integrating CCTA data directly into the Cath lab for live guidance during procedures.

What is the timeline for full deployment?

The project period runs from 2023-11-01 to 2027-10-31, suggesting a deployment window toward the end of 2027.

Consortium

Who built it

The consortium is heavily industry-led, with 5 industrial partners (including Philips as coordinator) representing a 36% industry ratio. This strong commercial presence, combined with 2 universities and 4 research centers across 6 countries, indicates a high focus on commercial viability and clinical translation rather than pure academic research.

How to reach the team

Contact Philips Medical Systems Nederland BV regarding the COMBINE-CT workflow

Next steps

Talk to the team behind this work.

Contact us to find licensing opportunities for AI-powered CCTA algorithms.

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