SciTransfer
CirculH2 · Project

Hydrogen-Powered Bio-Catalysts for Sustainable Chemical Production

manufacturingPilotedTRL 6

Imagine using hydrogen as a clean battery to power the tiny biological machines that make chemicals. Instead of using expensive or polluting additives to keep these machines running, this project uses hydrogen to drive the process. It's like swapping a dirty diesel engine for a clean electric one in a chemical factory.

By the numbers
6
Target Technology Readiness Level (TRL)
11
Total partners
64%
Industry ratio in consortium
The business problem

What needed solving

Industrial biotechnology currently relies on fossil-sourced or carbon-rich reactants and expensive cofactor recycling. This leads to high production costs, significant resource waste, and complex downstream processing.

The solution

What was built

A set of robust, scalable hydrogenase catalysts and specific alcohol dehydrogenases for producing Tulipalin A at the gram scale.

Audience

Who needs this

Specialty chemical manufacturersBio-based material producersIndustrial decarbonization consultantsGreen chemistry SMEs
Business applications

Who can put this to work

Specialty Chemicals
mid-size
Target: Fine chemical manufacturer

If you are a fine chemical manufacturer dealing with high production costs due to sacrificial reagents — this project developed robust hydrogenases that use H2 as a clean reactant. This reduces the need for carbon-rich additives and simplifies the cleaning process after production.

Biotechnology
SME
Target: Bio-based material producer

If you are a bio-based material producer dealing with inefficient cofactor recycling — this project developed a scalable H2-driven biotechnology. This allows for the production of specialty chemicals like Tulipalin A at the gram scale with minimal resource loss.

Industrial Chemistry
enterprise
Target: Commodity chemical plant

If you are a commodity chemical plant dealing with high energy usage and fossil-fuel dependence — this project developed catalysts that enable the decarbonization of industrial biotechnology. This makes the production of chemicals more economically competitive against fossil-sourced reactants.

Frequently asked

Quick answers

How does this impact production costs?

Based on available project data, it reduces costs by eliminating the need for excess sacrificial reagents and minimizing downstream processing due to high catalyst selectivity.

Can this be used at an industrial scale?

Yes, the project aims to demonstrate these hydrogenases in an industrial environment reaching TRL6, ensuring they are scalable and compatible with existing infrastructure.

What is the IP or licensing status?

Based on available project data, no specific licensing terms are mentioned, but the project involves 7 industrial partners, including 7 SMEs, suggesting a strong commercial focus.

How does it integrate with current factories?

The technology is designed to be compatible with existing industrial biotechnology infrastructure to facilitate a rapid transition to renewable resources.

What is the timeline for deployment?

The project runs from 2024-01-01 to 2027-12-31, aiming to reach TRL6 by the end of the period.

Consortium

Who built it

The consortium is heavily weighted toward commercial application, with an industry ratio of 64%. Out of 11 partners, 7 are SMEs and 7 are industrial entities, indicating that the research is being driven by market needs rather than purely academic curiosity. The collaboration spans 7 countries, providing a broad European base for industrial validation.

How to reach the team

Contact the Technical University of Munich (TUM) regarding the CirculH2 project.

Next steps

Talk to the team behind this work.

Contact us to connect with the CirculH2 consortium for pilot integration.

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