SciTransfer
CHIASMA · Project

Animal-Free Safety Testing Tools for Chemicals and Advanced Materials

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Imagine testing if a new chemical is safe without using animals, which is usually slow and expensive. Instead of labs with mice, this project uses computer simulations and tiny human-cell models to predict health risks. It's like having a digital twin of a human organ to see how a substance reacts before it ever leaves the factory.

By the numbers
15
experimental and computational NAMs advanced
70
regulatory stakeholders at the first Summit
23
consortium partners
The business problem

What needed solving

Traditional chemical safety testing is too slow, expensive, and ethically problematic due to heavy reliance on animal experiments. This creates a bottleneck for companies trying to launch sustainable materials quickly.

The solution

What was built

A suite of over 15 computer models and cell-based lab systems, and a Knowledge Graph for safety data.

Audience

Who needs this

Chemical manufacturersBattery material developersAgrochemical companiesRegulatory compliance officers
Business applications

Who can put this to work

Chemical Manufacturing
enterprise
Target: PFAS producer

If you are a chemical producer dealing with the persistence of 'forever chemicals' — this project developed New Approach Methodologies (NAMs) that provide reliable safety information without animal testing. This speeds up the validation of sustainable alternatives.

Agrochemicals
SME
Target: Nano-pesticide developer

If you are an agritech company dealing with safety questions regarding nano-pesticides — this project developed predictive computer models for nanoparticle effects on plants. This helps ensure your products meet environmental standards faster.

Energy Storage
mid-size
Target: Battery material manufacturer

If you are a manufacturer dealing with the safety of 2D materials for batteries — this project developed a safety assessment system that covers the entire life cycle from production to disposal. This reduces the risk of regulatory rejection.

Frequently asked

Quick answers

What is the cost or price for using these tools?

Based on available project data, no specific pricing or cost structures have been disclosed; the project focuses on providing accessible data for industry.

Can these methods be used at an industrial scale?

The project specifically aims for transferability to industrial environments and is demonstrating these methods on three major chemical groups to ensure they work in real-world settings.

How is the IP and licensing handled for the developed models?

Based on available project data, the specific licensing terms are not listed, but the goal is to provide accessible data for industry and public authorities.

Will these tools be accepted by government regulators?

Yes, the project includes regulators in its consortium and held a Regulatory Risk Assessors’ Summit with over 70 participants to ensure the methods are relevant to policy.

What is the timeline for implementation?

The project runs from 2024-01-01 to 2027-12-31, with initial tools and a knowledge graph already being developed in the first 18 months.

Consortium

Who built it

The consortium is well-balanced for technology transfer, consisting of 23 partners across 14 countries. While dominated by 11 universities and 6 research institutes, it maintains a 17% industry ratio with 4 companies (including 4 SMEs), ensuring that the scientific tools are developed with commercial viability and regulatory acceptance in mind.

How to reach the team

Contact the Luxembourg Institute of Science and Technology

Next steps

Talk to the team behind this work.

Contact us to find a partner for animal-free safety testing

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