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CEREBRO · Project

Non-invasive High-Resolution Brain Imaging Using an Electric Contrast Medium

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Imagine trying to listen to a conversation in a room through a thick concrete wall; that is how the skull blocks brain signals for doctors. This project creates a special 'electric dye' that can be introduced to the brain to amplify those signals. It allows doctors to see brain activity with crystal clarity without having to drill holes in the patient's head.

By the numbers
2,498,688
EU Contribution in EUR
5
Total partners
The business problem

What needed solving

Current high-resolution brain imaging requires drilling holes in the skull (trepanation), which is invasive and risky. Non-invasive scalp EEG exists but lacks the spatial accuracy needed for precise medical diagnostics.

The solution

What was built

A contrast-medium system consisting of a CMOS front-end architecture, digital-based amplifiers, and elongated magnetic nanorods for signal amplification.

Audience

Who needs this

Neurological medical device manufacturersBrain-computer interface (BCI) developersNeuroscience research institutesNanotechnology pharmaceutical companies
Business applications

Who can put this to work

Medical Device Manufacturing
enterprise
Target: Neurological imaging equipment producer

If you are a medical device company dealing with the trade-off between invasive surgery and low-resolution scalp EEG — this project developed a contrast-medium concept that provides high-accuracy imaging without skull trepanation.

Pharmaceuticals
mid-size
Target: Nanomedicine developer

If you are a biotech firm dealing with the delivery of functional particles to the brain — this project developed elongated magnetic nanorods that generate spectral replicas of neural signals.

Healthcare Services
any
Target: Specialized Neurosurgery Clinic

If you are a clinic dealing with the risks and recovery times of ECoG and StereoEEG implants — this project developed a non-invasive way to image the entire brain with the same accuracy as invasive methods.

Frequently asked

Quick answers

What is the estimated cost or price of the technology?

Based on available project data, there is no specific pricing or unit cost mentioned for the contrast medium or the hardware.

Can this be produced at an industrial scale?

The project has defined a compact CMOS front-end architecture and explored nanoparticle pathways, but industrial scaling data is not provided.

What is the IP and licensing status?

Based on available project data, specific patents or licensing terms are not listed, though the project is currently in the prototype and validation phase.

How does this integrate with existing EEG hardware?

The project developed a digital-based amplifier and CMOS front-end to translate low-frequency neural activity into higher-frequency bands for external detection.

What is the timeline for market availability?

The project period runs from 2022-09-01 to 2026-08-31, suggesting it is still in the development phase.

Consortium

Who built it

The consortium consists of 5 partners across 4 countries (AT, CH, FR, IT). It is heavily academic, with 4 universities and only 1 SME, resulting in an industry ratio of 20%. This suggests the project is currently driven by fundamental research and early-stage technical validation rather than immediate commercialization.

How to reach the team

Contact Politecnico di Torino regarding the CMOS front-end and nanoparticle prototypes.

Next steps

Talk to the team behind this work.

Contact us to find licensing opportunities for the CEREBRO contrast-medium technology.

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