If you are a medical device company dealing with the trade-off between invasive surgery and low-resolution scalp EEG — this project developed a contrast-medium concept that provides high-accuracy imaging without skull trepanation.
Non-invasive High-Resolution Brain Imaging Using an Electric Contrast Medium
Imagine trying to listen to a conversation in a room through a thick concrete wall; that is how the skull blocks brain signals for doctors. This project creates a special 'electric dye' that can be introduced to the brain to amplify those signals. It allows doctors to see brain activity with crystal clarity without having to drill holes in the patient's head.
What needed solving
Current high-resolution brain imaging requires drilling holes in the skull (trepanation), which is invasive and risky. Non-invasive scalp EEG exists but lacks the spatial accuracy needed for precise medical diagnostics.
What was built
A contrast-medium system consisting of a CMOS front-end architecture, digital-based amplifiers, and elongated magnetic nanorods for signal amplification.
Who needs this
Who can put this to work
If you are a biotech firm dealing with the delivery of functional particles to the brain — this project developed elongated magnetic nanorods that generate spectral replicas of neural signals.
If you are a clinic dealing with the risks and recovery times of ECoG and StereoEEG implants — this project developed a non-invasive way to image the entire brain with the same accuracy as invasive methods.
Quick answers
What is the estimated cost or price of the technology?
Based on available project data, there is no specific pricing or unit cost mentioned for the contrast medium or the hardware.
Can this be produced at an industrial scale?
The project has defined a compact CMOS front-end architecture and explored nanoparticle pathways, but industrial scaling data is not provided.
What is the IP and licensing status?
Based on available project data, specific patents or licensing terms are not listed, though the project is currently in the prototype and validation phase.
How does this integrate with existing EEG hardware?
The project developed a digital-based amplifier and CMOS front-end to translate low-frequency neural activity into higher-frequency bands for external detection.
What is the timeline for market availability?
The project period runs from 2022-09-01 to 2026-08-31, suggesting it is still in the development phase.
Who built it
The consortium consists of 5 partners across 4 countries (AT, CH, FR, IT). It is heavily academic, with 4 universities and only 1 SME, resulting in an industry ratio of 20%. This suggests the project is currently driven by fundamental research and early-stage technical validation rather than immediate commercialization.
Contact Politecnico di Torino regarding the CMOS front-end and nanoparticle prototypes.
Talk to the team behind this work.
Contact us to find licensing opportunities for the CEREBRO contrast-medium technology.