SciTransfer
CardioProtectMI · Project

New Drug to Prevent Heart Failure After Heart Attacks

healthTestedTRL 5

When doctors clear a blockage after a heart attack, the sudden rush of blood back into the heart can actually cause a second wave of damage. It's like a fire that was put out, but the water used to extinguish it causes a flood. This project is testing a medicine that calms this internal storm to stop the heart from failing permanently.

By the numbers
1.7M
Annual deaths from Ischemic Heart Disease in the EU
26M
Global prevalence of heart failure individuals
>20%
Potential reduction of post-MI heart failure
The business problem

What needed solving

Current heart attack treatments save lives but cause 'reperfusion injury' through inflammation, leading to chronic heart failure. This creates a massive burden on healthcare systems with over 26M affected people globally.

The solution

What was built

A drug candidate, RTP-026, and an approved clinical trial protocol for Phase IIa patient testing.

Audience

Who needs this

Cardiology pharmaceutical companiesAcute care hospital networksBiotech firms specializing in immunomodulatorsHealth insurance providers focused on chronic disease reduction
Business applications

Who can put this to work

Pharmaceuticals
enterprise
Target: Drug Development Firm

If you are a drug development firm dealing with the high mortality of ischemic heart disease — this project developed RTP-026 that could reduce post-MI heart failure by >20%. This provides a clear path to a high-demand therapeutic market.

Healthcare Providers
enterprise
Target: Hospital Network

If you are a hospital network dealing with the long-term costs of treating 26M global heart failure patients — this project developed a treatment to resolve inflammation during acute MI. This reduces the risk of patients transitioning into chronic heart failure.

Biotech
SME
Target: Immunotherapy Specialist

If you are a biotech company dealing with the challenge of reperfusion injury — this project developed an immunomodulating therapeutic. It validates the use of inflammation resolution to protect cardiac tissue.

Frequently asked

Quick answers

What is the estimated cost or price of the treatment?

Based on available project data, the specific cost or price per dose of RTP-026 is not disclosed.

Is the production ready for industrial scale?

The project is currently in Phase IIa clinical trials; based on available project data, industrial scale-up details are not yet provided.

What is the status of IP and licensing?

Based on available project data, the drug candidate RTP-026 is developed by ResoTher Pharma A/S, but specific licensing terms are not listed.

What is the timeline for market entry?

The project runs from 2024-02-01 to 2026-01-31, focusing on Phase IIa and IIb studies, meaning market entry follows these clinical validations.

How does the drug handle regulatory requirements?

The project has already finalized and received official approval for the Phase IIa clinical trial protocol from relevant regulatory bodies.

Consortium

Who built it

The project is led by a single partner, ResoTher Pharma A/S, a Danish SME. With a 100% industry ratio and no university or research institute partners, the project is lean and focused entirely on the commercial development and clinical validation of the drug candidate.

How to reach the team

Contact ResoTher Pharma A/S in Denmark regarding RTP-026 clinical trial partnerships.

Next steps

Talk to the team behind this work.

Contact us to track the Phase IIb proof of concept results for RTP-026.

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