SciTransfer
BIOMET4D · Project

4D Printed Biodegradable Implants That Change Shape to Expand Tissues

healthPrototypeTRL 3

Imagine a medical implant that acts like a slow-motion origami piece inside the body. Instead of multiple invasive surgeries to stretch skin or fix a skull, a single small device is put in and then unfolds on its own over time. Once the job is done, the metal simply dissolves away, leaving only healthy natural tissue behind.

By the numbers
1 in 2000
Live births affected by craniosynostosis
9
Consortium partners
The business problem

What needed solving

Reconstructive surgeries currently require multiple invasive procedures and painful maintenance (like weekly saline injections), leading to high healthcare costs and patient trauma.

The solution

What was built

A system of 4D smart metallic actuators and multi-domain optimization tools for creating biodegradable, shape-shifting implants.

Audience

Who needs this

Medical device manufacturersMaxillofacial surgery clinicsPlastic surgery equipment providersAdvanced 3D printing bureaus
Business applications

Who can put this to work

Medical Device Manufacturing
enterprise
Target: Orthopedic implant manufacturer

If you are an implant manufacturer dealing with the high cost of multi-stage reconstructive surgeries — this project developed 4D smart metallic actuators that allow for less invasive procedures and automatic shape changes. This reduces the need for repeated operating room visits.

Plastic Surgery & Dermatology
SME
Target: Specialized surgical equipment provider

If you are a provider dealing with the risks of infection and pain from manual saline injections in skin expanders — this project developed biodegradable shape-shifting implants that automate tissue expansion. This eliminates the need for weekly outpatient punctures.

Additive Manufacturing
mid-size
Target: 3D printing hardware and software developer

If you are a 3D printing company dealing with the limits of static implants — this project developed multi-domain optimization tools and powder bed laser fusion for multi-material degradable structures. This enables the production of load-bearing devices that evolve after implantation.

Frequently asked

Quick answers

What is the estimated cost or price of these implants?

Based on available project data, specific pricing is not mentioned, but the technology aims to reduce overall healthcare costs by minimizing the number of complex surgical procedures.

Can this be produced at an industrial scale?

The project utilizes powder bed laser fusion and additive manufacturing, which are scalable industrial processes, though the current focus is on proof-of-concept for specific clinical applications.

How is the intellectual property or licensing handled?

Based on available project data, specific licensing terms are not provided, but the consortium includes 3 SMEs and 3 industry partners who typically manage commercialization paths.

What is the timeline for clinical availability?

The project runs from 2022-07-01 to 2026-12-31, focusing on demonstrating proof-of-concept for craniosynostosis and skin expansion during this period.

How does this integrate with existing surgical workflows?

It replaces multi-step procedures with a single, less invasive implantation of a device that undergoes predesigned shape changes automatically.

Consortium

Who built it

The consortium is well-balanced for technology transfer, consisting of 9 partners across 5 countries. With a 33% industry ratio (3 companies, including 3 SMEs), there is a strong commercial bridge to the 4 universities and 1 research center involved, ensuring that the 4D printing research is aligned with market needs.

How to reach the team

Contact FUNDACION IMDEA MATERIALES in Spain

Next steps

Talk to the team behind this work.

Contact us to identify licensing opportunities for 4D biodegradable metals.

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