SciTransfer
B-Path · Project

Non-invasive Breath Sampling Devices for Rapid Respiratory Infection Screening and Diagnosis

healthTestedTRL 5

Imagine if you could detect a lung infection just by breathing into a device instead of using uncomfortable swabs. This project creates a way to catch germs from the air you exhale and test them quickly. It's like a high-tech filter that grabs the virus or bacteria so doctors can identify it without invasive procedures.

By the numbers
7 million
deaths from respiratory infections in 2020
7
of the last 9 pandemics caused by respiratory infections
The business problem

What needed solving

Current sampling methods for respiratory infections are often invasive or suboptimal, which hinders early detection and increases the economic risk of pandemics.

The solution

What was built

Two breath-based aerosol sampling devices, AveloCollect and AveloMask, along with associated molecular assays for pathogen detection.

Audience

Who needs this

Medical device manufacturersDiagnostic laboratory chainsPublic health screening agenciesPandemic preparedness organizations
Business applications

Who can put this to work

Medical Device Manufacturing
any
Target: Diagnostic hardware producer

If you are a diagnostic hardware producer dealing with the low patient acceptance of invasive swabs — this project developed AveloCollect and AveloMask devices that provide a non-invasive way to sample exhaled breath aerosols for faster screening.

Public Health & Pandemic Preparedness
enterprise
Target: Government health agency

If you are a government health agency dealing with the trillions of €s in economic losses caused by pandemics — this project developed a scalable sampling method that enables early detection and transmission control at all levels of care.

Clinical Diagnostics
mid-size
Target: Point-of-care testing lab

If you are a testing lab dealing with the need for rapid, multiplex detection of pathogens like influenza or tuberculosis — this project developed a system compatible with lateral-flow assays for immediate results.

Frequently asked

Quick answers

What is the cost or price of the sampling devices?

Based on available project data, specific pricing or unit costs for the AveloCollect and AveloMask devices are not provided.

Can these devices be produced at an industrial scale?

Yes, the project specifically aims to develop scalable devices, and the work performed includes a shift to staged production and shipment to align with clinical timelines.

Who owns the IP and how is licensing handled?

Based on available project data, the specific IP and licensing agreements are not detailed, though the consortium includes two industry partners.

How does this integrate with existing diagnostic tools?

The system is designed to work with molecular assays, viral metagenomics for novel pathogens, and point-of-care lateral-flow assays.

What is the timeline for market availability?

The project period runs from 2024-07-01 to 2028-06-30, suggesting the technology is currently in the development and clinical validation phase.

Consortium

Who built it

The consortium is well-balanced for commercialization, featuring a 29% industry ratio with 2 industrial partners and 1 SME. The collaboration spans 5 countries (DE, CH, IT, RO, ZA), combining academic research from 3 universities and 1 research institute with practical industrial production capabilities, as seen in the staged manufacturing of the AveloMask.

How to reach the team

Contact Universitätsklinikum Heidelberg

Next steps

Talk to the team behind this work.

Contact us to explore licensing opportunities for AveloCollect and AveloMask.

More in Health & Biomedical
See all Health & Biomedical projects