SciTransfer
ArtPlac · Project

Miniaturized Artificial Placenta for Integrated Lung and Kidney Support in Newborns

healthPrototypeTRL 3

Imagine a device that acts like a second placenta for babies born too early. Instead of using scary, oversized adult machines and tubes, it plugs directly into the belly button to handle breathing and waste filtering. This lets the baby recover naturally while staying close to their parents, avoiding the harsh side effects of traditional intensive care.

By the numbers
2.3 million
children dying within the first month of life globally
1 million
deaths attributed to preterm birth complications
6.7 billion
projected neonatal care devices market value by 2034 (USD)
1.2 million
newborns per year with improved survival chances
20-60%
patients experiencing major bleeding with current circuits
10-50%
patients suffering thrombotic events with current circuits
The business problem

What needed solving

Current neonatal life support devices are scaled-down adult versions that are too invasive and cause severe side effects. These devices often lead to fatal intracranial hemorrhages due to the high doses of anticoagulants required to prevent blood clots.

The solution

What was built

A miniaturized all-in-one artificial placenta prototype that combines lung oxygenation and kidney dialysis, featuring biomimetic surface coatings to prevent blood clots.

Audience

Who needs this

Neonatal ICU equipment manufacturersBiomedical coating specialistsPediatric specialty hospitalsMedical catheter producers
Business applications

Who can put this to work

Medical Device Manufacturing
enterprise
Target: Neonatal Intensive Care Unit (NICU) equipment manufacturer

If you are a manufacturer dealing with the lack of baby-specific life support—since current tools are just scaled-down adult versions—this project developed a miniaturized all-in-one device that integrates lung and kidney functions. This allows you to enter a neonatal care market projected to exceed USD 6.7 billion by 2034.

Biomaterials
mid-size
Target: Specialized polymer and coating producer

If you are a chemical company dealing with high thrombosis rates in blood-contacting devices, where 10-50% of patients suffer thrombotic events, this project developed biomimetic surface coatings like nitric oxide-releasing polymers. This technology reduces the need for risky systemic anticoagulation in fragile newborns.

Healthcare Systems
enterprise
Target: Private hospital group specializing in maternity and neonatology

If you are a healthcare provider dealing with high morbidity and long hospital stays for preterm infants, this project developed a plug-in support system via the umbilical cord. This reduces invasive procedures and promotes family-integrated care, potentially improving survival chances for up to 1.2 million newborns yearly.

Frequently asked

Quick answers

What is the estimated cost or price of the device?

Based on available project data, the specific unit cost or pricing strategy is not provided.

Is the technology ready for industrial scale production?

The project is currently in the prototype and validation phase, focusing on miniaturization and hemocompatibility before moving to full industrial scale.

What is the IP or licensing status of the surface coatings?

Based on available project data, specific patent or licensing details are not listed, though the project focuses on developing biomimetic coatings including zwitterionic functionalization.

How does the device integrate into existing NICU workflows?

It integrates by connecting to the newborn's belly button using expandable catheters, allowing the baby to breathe and feed naturally while receiving support.

What is the timeline for clinical application?

The project period runs from 2023-04-01 to 2027-03-31, indicating the development and validation phase ends in early 2027.

Consortium

Who built it

The consortium is heavily research-driven, consisting of 11 partners across 6 countries. With 6 universities and 1 research institute, the academic weight is high, while industry presence is limited to 2 partners (18% ratio). This structure suggests the project is currently focused on high-risk technical validation rather than immediate commercial rollout.

How to reach the team

Contact KLINIKUM NURNBERG in Germany for technical inquiries.

Next steps

Talk to the team behind this work.

Contact SciTransfer to identify licensing opportunities for the biomimetic coatings.

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