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ACU-SERS · Project

Rapid Point-of-Care Antibiotic Monitoring Device for Intensive Care Units

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Imagine a fast-acting blood test that works like a digital fingerprint scanner for medicine. Instead of sending samples to a distant lab and waiting hours, doctors can check antibiotic levels right at the bedside in 15 minutes. This helps them adjust doses instantly to save lives and prevent drug resistance.

By the numbers
700k
deaths from sepsis in Europe each year
50%
sepsis patients with inappropriate antibiotic dosing
15 minutes
time to provide quantitative antibiotic drug level concentration
The business problem

What needed solving

Current antibiotic monitoring in ICUs is too slow and expensive, leading to inappropriate dosing for 50% of sepsis patients. This results in higher mortality, toxicity, and increased antibiotic resistance.

The solution

What was built

An automated PoC device featuring a centrifugal microfluidics cartridge and a label-free SERS chip reader for rapid drug quantification.

Audience

Who needs this

ICU Department HeadsIVD Device ManufacturersClinical Diagnostic LabsPharmaceutical R&D Firms
Business applications

Who can put this to work

Medical Diagnostics
enterprise
Target: IVD Device Manufacturer

If you are an IVD manufacturer dealing with slow lab-based drug monitoring — this project developed a microfluidics cartridge and SERS reader that provides antibiotic concentrations in 15 minutes. This allows for a transition from centralized labs to bedside testing.

Healthcare Providers
enterprise
Target: Private Hospital Group

If you are a hospital group dealing with high sepsis mortality and inappropriate dosing in 50% of patients — this project developed an automated PoC device that optimizes patient treatments. This reduces adverse events and improves ICU efficiency.

Pharmaceutical Research
mid-size
Target: Drug Development Firm

If you are a pharma company dealing with the need for precise drug level quantification during trials — this project developed a label-free SERS sensor platform. This provides a flexible and scalable way to monitor various drug types beyond antibiotics.

Frequently asked

Quick answers

What is the cost or price of the device?

Based on available project data, specific pricing is not mentioned, but the system is described as a cost-effective alternative to current slow and expensive workflows.

Can this be produced at an industrial scale?

Yes, the project focuses on enhancing sensor uniformity and preparation to make scaling up production possible.

What is the IP and licensing strategy?

The project aims to found a spin-off company to commercialize the technology and eventually seek a global distribution deal with a large diagnostics company.

How does it integrate into current hospital workflows?

It is designed as a benchtop device with a microfluidics cartridge for seamless integration into ICUs and decentralized healthcare settings.

What is the timeline for market entry?

The project runs from 2024-05-01 to 2027-04-30, with the goal of making the technology investment-ready and generating early revenues via a spin-off.

Consortium

Who built it

The consortium is highly concentrated, consisting of a single academic partner (Danmarks Tekniske Universitet) from one country (Denmark). With 0% industry representation currently, the project is driven by university research, though it explicitly aims to transition into a commercial spin-off.

How to reach the team

Contact the Technical University of Denmark (DTU) regarding the ACU-SERS spin-off

Next steps

Talk to the team behind this work.

Contact us to connect with the ACU-SERS team for licensing or investment opportunities.

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