ALIVER developed the DIALIVE liver dialysis device, and CARBALIVE explored nanoporous carbon for liver treatment — both targeting patients who need alternatives to transplantation.
YAQRIT LIMITED
UK SME developing liver dialysis devices, carbon-based therapeutics, and immunological treatments for acute and chronic liver failure.
Their core work
YAQRIT is a UK-based SME focused on developing therapeutic devices and treatments for severe liver disease, particularly acute-on-chronic liver failure. They specialize in liver dialysis technology, extracorporeal liver assist devices, and advanced carbon-based materials for treating liver cirrhosis and related conditions. Their work spans from nanoporous carbon therapeutics to pharmacological interventions combining growth factors with immune modulation, positioning them as a translational medicine company bridging material science and hepatology.
What they specialise in
CARBALIVE specifically evaluated carbons of controlled porosity as a therapeutic for liver cirrhosis and NAFLD.
Both ALIVER and A-TANGO directly target acute-on-chronic liver failure, with A-TANGO combining G-CSF and toll-like receptor modulation.
A-TANGO explores G-CSF combined with TAK-242 (toll-like receptor 4 antagonist), marking a shift toward pharmacological immune modulation strategies.
How they've shifted over time
YAQRIT's early work (2015-2017) centered on material science applied to liver disease — specifically nanoporous carbon as a therapeutic platform for cirrhosis and fatty liver disease (CARBALIVE). By 2017-2021, they moved into medical device development with the DIALIVE liver dialysis system (ALIVER). Their most recent project (A-TANGO, 2021-2026) represents a further shift toward pharmacological and immunological approaches, combining growth factor therapy with toll-like receptor antagonism — moving from devices to drug-based interventions.
YAQRIT is evolving from materials and devices toward pharmacological interventions for liver failure, suggesting growing capability in drug development and immune modulation — a direction likely to expand into clinical trial partnerships.
How they like to work
YAQRIT consistently participates as a partner rather than leading consortia, which is typical for a specialized SME contributing deep domain expertise to larger research efforts. With 32 unique partners across 10 countries in just 3 projects, they operate within large, diverse consortia — indicating they are comfortable in complex multi-partner environments. Their consistent role as participant suggests they bring specific technical capabilities (devices, materials, clinical know-how) rather than managing overall project direction.
YAQRIT has built a broad European network of 32 partners across 10 countries through just 3 projects, reflecting involvement in large health research consortia. Their collaborative reach is notably wide for an SME of this size.
What sets them apart
YAQRIT occupies a rare niche at the intersection of material science, medical devices, and pharmacology — all applied specifically to liver failure. Unlike academic hepatology groups, they bring commercial product development focus to liver dialysis and therapeutic interventions. For consortium builders, they offer a specialized SME partner with proven H2020 experience and deep expertise in a disease area (liver failure) that has very few dedicated commercial players in Europe.
Highlights from their portfolio
- ALIVERLargest funding (EUR 2.8M) and developed DIALIVE, a tangible liver dialysis device — their most product-oriented project.
- A-TANGOMost recent and longest-running project (2021-2026), signaling a strategic pivot toward drug-based immunomodulation for liver failure.
- CARBALIVETheir earliest H2020 project, establishing their foundation in nanoporous carbon materials applied to liver disease.