SciTransfer
Organization

UNIVERSITATKLINIKUM LEIPZIG

German university hospital contributing as a clinical site to H2020 cardiovascular trials on heart failure pharmacology and aortic aneurysm surgery.

University hospitalhealthDEThin data (2/5)
H2020 projects
3
As coordinator
0
Total EC funding
Unique partners
70
What they do

Their core work

University Hospital Leipzig (UKL) is a large German academic medical center that delivers patient care, trains physicians, and runs clinical research — particularly multi-center randomized trials. In its H2020 footprint, it acted as a clinical site contributing patients, cardiovascular expertise, and trial infrastructure to cardiac and vascular studies coordinated by other institutions. It also participated in a doctoral training network on mass-spectrometry-based protein lipid adduct analysis, signalling an analytical chemistry interface with its clinical work. In short: a university hospital that runs trials and hosts research training rather than one that leads basic-science consortia.

Core expertise

What they specialise in

2 projects

BETA3_LVH ran a multi-center placebo-controlled trial of the beta3-adrenergic agent mirabegron for cardiac hypertrophy, and PAPA-ARTIS is a randomized trial on paraplegia prevention in aortic aneurysm repair.

Aortic aneurysm and vascular surgery researchsecondary
1 project

PAPA-ARTIS focuses on thoracoabdominal aortic aneurysm repair with minimally-invasive staged spinal cord protection.

Cardiac hypertrophy and diastolic dysfunctionsecondary
1 project

BETA3_LVH investigates mirabegron's effect on left ventricular hypertrophy and diastolic function.

Mass spectrometry / protein-lipid adduct analysisemerging
1 project

UKL was a partner in the MASSTRPLAN MSCA-ITN doctoral training network on mass-spectrometry-based protein lipid adduct analysis.

Multi-center clinical research infrastructureprimary
2 projects

Recurring third-party/clinical-site role in BETA3_LVH and PAPA-ARTIS shows established capacity to enrol patients and contribute to randomized controlled trials.

Evolution & trajectory

How they've shifted over time

Early focus
Cardiac pharmacology trials
Recent focus
Aortic surgery trials

Earlier H2020 engagement (2015 starts) centred on cardiac hypertrophy, diastolic dysfunction and beta3-adrenergic pharmacology via BETA3_LVH, plus mass-spectrometry training in MASSTRPLAN. By 2017 the focus shifted to vascular surgery through PAPA-ARTIS, emphasising thoracoabdominal aortic aneurysm repair and spinal cord protection. The through-line is randomized controlled trials in cardiovascular medicine; the organ system moved from myocardium to aorta.

Momentum is clearly toward multi-center vascular-surgery trials, making UKL a candidate clinical site for future consortia in aortic disease, peri-operative neuroprotection, and cardiovascular device studies.

Collaboration profile

How they like to work

Role: third_party_expertReach: European15 countries collaborated

UKL has never coordinated an H2020 project in this dataset — it participates as a third party or partner, typical of a clinical recruiting site. Across just three projects it connects with 70 partners in 15 countries, reflecting the large consortia built around multi-center RCTs. Expect a reliable clinical contributor rather than a scientific lead.

Connected to 70 unique partners across 15 countries within only three projects, a footprint characteristic of large multi-center clinical trial consortia. Orientation is European, with no visible single dominant bilateral partner country beyond the typical Western-European trial networks.

Why partner with them

What sets them apart

Among German public-health bodies in H2020, UKL stands out for anchoring two substantial cardiovascular RCTs (BETA3_LVH and PAPA-ARTIS) while also training doctoral researchers in bioanalytical mass spectrometry. Partners get a university hospital with genuine cardiology and vascular-surgery depth plus a history of handling complex trial protocols. It is the right partner for clinical validation, not for leading a scientific consortium.

Notable projects

Highlights from their portfolio

  • PAPA-ARTIS
    Long-running (2017-2024) randomized trial on paraplegia prevention during thoracoabdominal aortic aneurysm repair — an unusually specific surgical-neuroprotection topic and UKL's most recent engagement.
  • BETA3_LVH
    Multi-center placebo-controlled trial repurposing the overactive-bladder drug mirabegron for cardiac hypertrophy, an uncommon drug-repurposing cardiology study.
  • MASSTRPLAN
    An MSCA-ITN doctoral training network, showing UKL's willingness to host early-stage researchers in analytical chemistry adjacent to clinical medicine.
Cross-sector capabilities
clinical trial coordination and patient recruitmentanalytical chemistry / mass spectrometrymedical device evaluation in vascular surgerydoctoral training and biomedical education
Analysis note: Only 3 H2020 projects with UKL always in a non-leading role (third party or partner) and no EC funding figures available, so conclusions about scale and coordination capacity are cautious; cardiovascular-trial focus is clearly supported, other areas are inferred from single projects.