Core contributor in BIOCASCADES, ES-Cat, LightZymes, ProteinFactory, Secreters, RADICALZ, and MS SPIDOC — spanning biocatalysis, directed evolution, and enzyme discovery.
UNIVERSITAET GREIFSWALD
German university strong in protein engineering, synthetic biology, and microbial biotechnology, with growing focus on plastic waste upcycling and metagenomics.
Their core work
Universität Greifswald is a German research university with deep strength in protein engineering, enzyme design, and microbial biotechnology. Their labs work on programming microorganisms to produce valuable chemicals, degrade plastics, and catalyze industrial reactions — bridging fundamental biochemistry with applied bioprocessing. They also contribute specialized expertise in plasma physics for space propulsion and advanced mass spectrometry for structural biology. Across 23 H2020 projects, they consistently serve as the biotechnology and protein science partner in large European consortia.
What they specialise in
Key partner in SynBio4Flav (synthetic microbial consortia for flavonoids), MIX-UP (mixed plastics biodegradation), upPE-T (bioplastic upcycling), and RADICALZ (enzyme discovery via metagenomics).
Growing cluster of projects: MIX-UP tackles mixed plastic waste with microbial communities, upPE-T converts PE/PET into biodegradable bioplastics, and COSMOS explored bio-based oleochemicals.
Contributed plasma diagnostics and modelling expertise to both HEMPT-NG and HEMPT-NG2 projects developing next-generation plasma thrusters.
PROSPECTOMICS applies metagenomics and machine learning to hydrocarbon prospecting; RADICALZ uses metagenomics for enzyme discovery; HoloRuminant studies ruminant microbiomes.
Coordinated PredicTOOL on protein immunogenicity, participated in AGePOP on geriatric drug absorption, and in CHILI on HPV screening in low-income countries.
How they've shifted over time
In their early H2020 period (2015–2018), Greifswald focused on foundational protein science — biocatalytic cascades, protein secretion systems, and artificial enzyme design — alongside a niche in plasma physics for space propulsion. From 2019 onward, their work shifted decisively toward synthetic biology, microbial consortia engineering, and environmental biotechnology, particularly plastic waste upcycling and metagenomics-driven enzyme discovery. The addition of machine learning as a recurring keyword signals their labs are integrating computational methods into their wet-lab biotechnology pipeline.
Greifswald is converging on computationally-guided microbial engineering for circular economy applications — expect future projects combining metagenomics, machine learning, and metabolic engineering to tackle waste valorization and sustainable biomanufacturing.
How they like to work
Greifswald overwhelmingly participates as a specialist partner rather than leading consortia (21 of 23 projects as participant, only 2 as coordinator). With 222 unique partners across 36 countries, they are highly networked and comfortable in large, diverse consortia — the kind of reliable technical partner that coordinators seek out for biotechnology and protein science expertise. Their repeated participation in MSCA training networks (5 projects) also marks them as an institution invested in doctoral training and knowledge transfer.
Extensive European network spanning 222 unique consortium partners across 36 countries, reflecting broad geographic reach well beyond Germany. Their frequent involvement in Marie Skłodowska-Curie training networks gives them particularly strong ties to academic partners across the EU.
What sets them apart
Greifswald occupies a distinctive niche as a mid-sized German university that punches above its weight in microbial and protein biotechnology — their combination of enzyme engineering, synthetic biology, and metagenomics expertise in a single institution is relatively rare. They bring both fundamental science depth (ERC grants, MSCA networks) and applied biotech capability (plastic upcycling, industrial enzyme discovery), making them equally suited for basic research consortia and innovation-driven projects. Their unusual side expertise in plasma propulsion also makes them a versatile partner for interdisciplinary calls.
Highlights from their portfolio
- LightZymesLargest single EC contribution (EUR 1.3M) — developing artificial enzymes with unnatural cofactors for light-driven reactions, representing their deepest investment in frontier enzyme engineering.
- MIX-UPFlagship circular economy project (EUR 720K) using microbial communities to biodegrade and upcycle mixed plastics — directly addresses the plastic crisis with industrial relevance.
- PredicTOOLOne of only two projects Greifswald coordinated, focused on understanding protein immunogenicity using nanomethods — shows their capacity to lead when the topic aligns with core protein science strengths.