Coordinated TK-NEO, developing personalized cancer immunotherapy through DNA electroporation vaccines.
TAKIS SRL
Italian biotech SME developing DNA-based cancer immunotherapy and contributing to gene therapy and targeted drug delivery research.
Their core work
Takis is a Rome-based biotech SME specializing in cancer immunotherapy and advanced therapeutic development. Their core work centers on DNA electroporation (DNA-EP) vaccine platforms for personalized cancer treatment, while also contributing to targeted drug delivery and gene/cell therapy research for rare diseases. They bridge preclinical research and early-stage therapeutic development, operating at the intersection of immunology, oncology, and advanced therapy medicinal products (ATMPs).
What they specialise in
Participated in Magicbullet Reloaded, working on small molecule-drug conjugates and peptide-drug conjugates for tumor-targeted therapy.
Participant in ARDAT, a large-scale initiative accelerating research and development for advanced therapies including gene and cell therapy.
Both ARDAT and TK-NEO involve advanced therapeutic modalities — gene therapy, cell therapy, and DNA-based immunotherapy platforms.
How they've shifted over time
Takis entered H2020 in 2019 with a focused bet on personalized cancer immunotherapy (TK-NEO, SME Phase 1), signaling early commercial ambitions around their DNA-EP vaccine platform. Their subsequent projects broadened into targeted drug conjugates (Magicbullet Reloaded) and gene/cell therapy for rare diseases (ARDAT), indicating a deliberate expansion from oncology-only toward the wider advanced therapies space. This trajectory suggests a company moving from a single product concept toward becoming a broader platform contributor in therapeutic biologics.
Takis is expanding from cancer vaccines into the broader advanced therapies ecosystem, positioning itself as a specialist contributor in gene therapy and targeted drug delivery — sectors with growing EU funding and regulatory attention.
How they like to work
Takis operates primarily as a participant in larger consortia (2 of 3 projects), joining research-intensive networks like Magicbullet Reloaded (MSCA training network) and ARDAT (major RIA). Their one coordination was a small SME Phase 1 feasibility study, typical for biotech SMEs validating a commercial concept. With 49 unique partners across just 3 projects, they are embedded in large collaborative networks rather than leading them — a common and effective pattern for specialist SMEs contributing deep domain expertise to multi-partner efforts.
Despite only 3 projects, Takis has collaborated with 49 unique partners across 15 countries, reflecting their participation in large pan-European consortia. Their network spans broadly across the EU with no single dominant geographic cluster beyond their Italian base.
What sets them apart
Takis combines hands-on biotech R&D capability with EU project experience in a niche that few SMEs occupy: the development of DNA-based immunotherapy platforms and advanced therapeutic products. For consortium builders, they offer a rare profile — a small, agile Italian biotech that can contribute both proprietary technology (DNA-EP vaccines) and practical experience across multiple therapeutic modalities including targeted drug conjugates and gene therapy. Their SME status also strengthens proposal scoring for calls requiring industrial and SME participation.
Highlights from their portfolio
- TK-NEOTheir only coordinated project — an SME Phase 1 feasibility study for personalized cancer immunotherapy, revealing their core commercial ambition around DNA-EP vaccines.
- ARDATA major RIA running until 2026 focused on accelerating advanced therapies (gene/cell therapy for rare diseases), representing their largest single funding (EUR 225K) and longest commitment.
- Magicbullet ReloadedAn MSCA training network on targeted drug conjugates for tumor therapy, showing Takis contributes to research training alongside established academic partners.