CLATHROPROBES (2018-2023) is entirely built on clathrochelate synthesis and their application as optical and magnetic probes.
SRL POLIVALENT-95
Moldovan chemistry SME synthesising cage metal complexes and optical probes for protein detection in EU research consortia.
Their core work
SRL POLIVALENT-95 is a Moldovan private company with specialist expertise in synthetic inorganic and supramolecular chemistry, particularly the preparation of cage-type metal complexes (clathrochelates) and spin-active coordination compounds. In the MSCA-RISE framework they function as a host institution for international researcher exchanges, providing wet-chemistry laboratory capacity — synthesis, spectroscopic characterization (NMR, IR, circular dichroism, fluorescence) — to multinational research networks. Their most recent work targets biosensing applications: designing chiroptical and optical molecular probes capable of detecting specific proteins such as albumins. They are a niche chemistry contributor embedded in European academic consortia, bringing Eastern European synthetic chemistry capacity at SME cost.
What they specialise in
SPINSWITCH (2017-2021) is dedicated to multifunctional spin crossover coordination materials.
CLATHROPROBES keywords include circular dichroism, fluorescence, NMR, and IR — the full spectroscopic toolkit used to characterize probe behaviour.
CLATHROPROBES explicitly targets protein and albumin detection using cage-complex probes, placing the organisation at the chemistry-biology interface.
How they've shifted over time
In their first recorded H2020 project (SPINSWITCH, 2017) the organisation was engaged with spin crossover materials — coordination compounds that switch between magnetic states, relevant to molecular switches and data storage. By 2018 their second project (CLATHROPROBES) pivoted toward cage metal complexes applied to biological sensing, introducing an entirely different keyword set centred on proteins, albumins, probes, and chiroptical techniques. The shift is notable: from functional materials with physics-adjacent applications toward analytical chemistry and biosensing, indicating a broadening into life-science-adjacent research.
The organisation is moving from pure materials chemistry toward applied biosensing, making them a plausible partner for consortia combining synthetic chemistry with medical diagnostics or analytical instrumentation.
How they like to work
POLIVALENT-95 has participated exclusively as a consortium partner — never as project coordinator — across both recorded projects. Both participations are under MSCA-RISE, a mobility scheme that rewards institutions approved to host incoming researchers rather than lead intellectual agendas; this suggests their role is to provide laboratory infrastructure and synthetic chemistry know-how within larger academic networks. With 12 unique partners spread across 8 countries from just 2 projects, they are connected to relatively broad networks for an organisation their size.
Despite only two projects, POLIVALENT-95 has collaborated with 12 distinct partner organisations across 8 countries, entirely through MSCA-RISE consortia — multi-institutional exchange networks that typically involve 6-10 partners per project. Their reach is European but anchored in academic chemistry groups rather than industry.
What sets them apart
POLIVALENT-95 is one of very few Moldovan private companies with verified H2020 participation in advanced coordination chemistry, making them a rare Eastern European SME host for MSCA researcher exchanges in this niche. Their combination of clathrochelate synthesis capacity and spectroscopic characterisation infrastructure (circular dichroism, fluorescence, NMR) is not commonly found outside university settings, and their SME status makes them more agile and lower-overhead than an academic partner. For a consortium needing synthetic chemistry capacity east of the EU border at SME rates, they represent an unusual and practical option.
Highlights from their portfolio
- SPINSWITCHThe larger of the two projects (EUR 126,000) and their first H2020 entry, focused on multifunctional spin crossover materials — a topic with potential applications in molecular electronics and data storage.
- CLATHROPROBESIntroduced the organisation to biological sensing via cage metal complex probes, the most applied and commercially-adjacent work in their portfolio, running until 2023.