Core thread across TBVAC2020, VAC2VAC, RABYD-VAX, TRANSVAC-DS, Inno4Vac, DEFEND, and ERA4TB — spanning TB, rabies, African swine fever, and vaccine manufacturing infrastructure.
SCIENSANO
Belgium's national public health institute specializing in vaccine quality, genomic diagnostics, health data infrastructure, and One Health research across 53 countries.
Their core work
Sciensano is Belgium's national public health institute, combining human health, animal health, and food safety research under a single "One Health" mandate. They develop and validate vaccines, diagnostic tools (including next-generation sequencing for oncology), and certified reference materials for biological toxin detection. They operate as a key node in European health data infrastructures, coordinating population health information systems and contributing metrology expertise in food and nutrition. Their work bridges laboratory science with public health policy — from human biomonitoring of chemical exposures to cervical cancer screening models.
What they specialise in
Coordinated PHIRI (population health information research infrastructure) and participated in unCoVer, RESISTIRE, and HealthyCloud — all focused on health data standardization and pandemic evidence systems.
EuroBioTox established validated procedures for biological toxin identification; METROFOOD-RI added metrology in food and nutrition.
HBM4EU on chemical mixture exposure biomarkers, Imptox on microplastics toxicity, and ALTERNATIVE on chemical mixture effects on cardiac tissue.
Coordinates oncNGS (their largest project at EUR 8.4M) on next-generation sequencing for oncology diagnostics, complemented by RISCC on risk-based cervical cancer screening.
One Health EJP on foodborne zoonoses and antimicrobial resistance, DEFEND on emerging animal diseases, and B-GOOD on bee health monitoring.
How they've shifted over time
In the early period (2015–2018), Sciensano focused on classical public health laboratory work: vaccine quality control (VAC2VAC), human biomonitoring of chemical exposures (HBM4EU), biological toxin standardisation (EuroBioTox), and One Health zoonoses. From 2020 onward, their portfolio shifted sharply toward health data infrastructures and genomics-driven diagnostics — coordinating PHIRI for population health data during COVID-19, launching oncNGS as their flagship in NGS-based cancer diagnostics, and joining digital health initiatives like HealthyCloud. The evolution shows a clear move from wet-lab reference work toward data-intensive, digitally-enabled public health research.
Sciensano is increasingly positioning itself as a health data infrastructure hub with growing capacity in genomics and digital diagnostics, making them a strong partner for future projects combining clinical data with molecular analysis.
How they like to work
Sciensano operates predominantly as an active partner (20 of 25 projects), contributing specialist expertise to large European consortia rather than leading them. When they do coordinate, they take on infrastructure-scale projects — oncNGS (EUR 8.4M) and PHIRI (EUR 1.3M) are both platform-building efforts. With 596 unique partners across 53 countries, they are a well-connected network hub, comfortable working in large multi-country consortia typical of European Joint Programmes and research infrastructure projects.
Sciensano has collaborated with 596 unique partners across 53 countries, making them one of the most broadly connected health research institutions in H2020. Their network spans all of Europe with significant global reach through pandemic-response and One Health programmes.
What sets them apart
Sciensano's distinctive strength is their integration of regulatory-grade laboratory work (certified reference materials, vaccine quality testing, diagnostic validation) with large-scale health data infrastructure coordination. Few organizations in Europe combine wet-lab metrology expertise with the ability to build and run population-level data platforms. For consortium builders, they offer a rare package: a national public health institute that can both generate validated laboratory data and connect it to European health information networks.
Highlights from their portfolio
- oncNGSTheir largest project (EUR 8.4M) and a coordination role — building European-wide NGS diagnostics standards for oncology, signalling a major strategic commitment to genomic medicine.
- PHIRICoordinated the EU's population health information infrastructure during COVID-19, establishing Sciensano as a go-to partner for cross-border health data harmonization.
- One Health EJPEUR 1.85M contribution to the flagship European Joint Programme bridging human health, animal health, and food safety — embodying Sciensano's core One Health mission.