PROZOMIX LIMITED

Their core work

Prozomix is a UK-based SME specializing in enzyme production and biocatalysis. They supply diverse enzyme panels — including lyases, aldolases, transketolases, and halohydrin dehalogenases — for industrial applications such as pharmaceutical synthesis and bulk chemical manufacturing. Their core business is providing ready-to-use enzyme libraries and engineering enzymes for improved thermostability and activity, enabling greener chemical processes that replace traditional organic chemistry with biological catalysts.

What they specialise in

How they've shifted over time

In their early H2020 period (2015–2018), Prozomix focused broadly on building enzyme platforms — assembling panels of C-C bond forming enzymes (aldolases, lyases, halohydrin dehalogenases), engineering them for thermostability, and testing them in microreactors and cascade reactions for API and bulk chemical synthesis. By 2021, their focus narrowed and deepened: CC-TOP targets specifically top-performing carboligation enzymes, with emphasis on protein engineering, enzyme promiscuity, and asymmetric synthesis — a shift from broad platform-building to precision enzyme optimization for selective chemistry.

Prozomix is moving from general enzyme supply toward highly specialized, engineered biocatalysts for selective organic synthesis — expect future work in pharmaceutical intermediates and fine chemicals.

How they like to work

Prozomix consistently participates as a specialist partner rather than leading consortia — zero projects as coordinator across all four H2020 involvements. They work in mid-to-large consortia (38 unique partners across 9 countries), suggesting they are a valued niche contributor brought in for their enzyme expertise. Their role is that of a commercial enzyme supplier and technical partner who provides the biological tools other partners need for their research.

Prozomix has collaborated with 38 unique partners across 9 countries, indicating a well-connected European network despite being a small company. Their partnerships span academia and industry across the biocatalysis community.

What sets them apart

Prozomix occupies a rare niche as a commercial SME that manufactures and supplies diverse enzyme panels directly to research and industrial partners. Unlike university labs that study enzymes or large chemical companies that use them, Prozomix bridges the gap — they are the enzyme supplier that makes biocatalysis projects practically feasible. For any consortium needing ready-to-screen enzyme libraries or custom-engineered biocatalysts, Prozomix brings a catalogue and production capability that most academic partners cannot match.

Highlights from their portfolio

• CARBAZYMES
  Foundational project establishing their C-C bond enzyme platform across multiple enzyme classes, with direct industrial targets (APIs, bulk chemicals, cascade reactions).
• CC-TOP
  Most recent project (2021–2025) showing their evolution toward precision protein engineering and asymmetric synthesis — signals their current strategic direction.
• METAFLUIDICS
  Largest single EC contribution (EUR 546,806) and broadened their capability into metagenomic screening for novel enzyme discovery.