Both WEAKID (wearable dialysis machine) and CORDIAL (portable continuous peritoneal dialysis) directly involve miniaturized dialysis hardware for patient-facing use.
NANODIALYSIS BV
Dutch medtech SME developing portable peritoneal dialysis systems with dialysate regeneration for home-use kidney failure treatment.
Their core work
NANODIALYSIS BV is a Dutch medical technology SME specializing in miniaturized and portable dialysis systems for patients with kidney failure. Their work centers on making dialysis treatment accessible outside the hospital — through wearable devices and home-use peritoneal dialysis systems with on-board dialysate regeneration. They contribute clinical validation expertise and device development knowledge to research consortia, bridging the gap between laboratory prototypes and real-world patient use. Their focus is on freeing kidney patients from fixed dialysis infrastructure by engineering systems small and reliable enough for daily life.
What they specialise in
CORDIAL (2021–2025) focuses specifically on continuous-flow peritoneal dialysis with integrated dialysate regeneration, a technically distinct modality from hemodialysis.
CORDIAL explicitly targets continuous dialysate regeneration and personalised dialysate formulation, enabling closed-loop dialysis without large fluid volumes.
Both projects are named clinical validation efforts — WEAKID and CORDIAL both carry 'clinical validation' in their full titles, indicating this is a core organisational capability.
CORDIAL keywords explicitly include 'home-use', signalling a patient empowerment orientation that shapes device design and clinical trial design alike.
How they've shifted over time
NANODIALYSIS entered H2020 through WEAKID (2017–2019) working on a miniature wearable hemodialysis machine — a hardware-first approach to ambulatory kidney replacement. Their second project, CORDIAL (2021–2025), shifted modality entirely to peritoneal dialysis and introduced a more sophisticated technical challenge: continuous dialysate regeneration and personalisation, which removes the need for pre-made dialysate bags. The trajectory shows a move from wearable hardware miniaturisation toward closed-loop fluidic systems — suggesting growing competence in the chemistry and engineering of dialysate management, not just device form factor.
NANODIALYSIS is moving toward fully self-contained, home-use dialysis systems with integrated fluid regeneration — a direction that aligns with the broader nephrology field's push to reduce hospital dependency for chronic kidney disease patients.
How they like to work
NANODIALYSIS has participated in both projects as a partner, never as coordinator, which suggests they operate as a specialist technology contributor rather than a project integrator. Their consortia are small — just 6 unique partners across both projects — indicating focused, tight-knit research teams rather than large multi-stakeholder programs. This profile suits organisations looking for a technically deep, committed partner on a specific device or clinical challenge, not a generalist consortium builder.
NANODIALYSIS has collaborated with 6 unique partners across 4 countries, a narrow but international footprint typical of niche medical device SMEs. Their network is European in scope but small by H2020 standards, suggesting they select partners carefully around shared clinical and engineering goals.
What sets them apart
NANODIALYSIS sits at a rare intersection: a private company with hands-on clinical validation experience in both hemodialysis and peritoneal dialysis miniaturisation. Most players in this space are either large medtech corporations or academic nephrology groups — NANODIALYSIS offers the agility of an SME with domain depth that comes only from sustained, funded device development. For a consortium targeting home dialysis, wearable kidney support, or dialysate management innovation, they bring both the device knowledge and the clinical trial credibility that pure engineering firms lack.
Highlights from their portfolio
- CORDIALThe largest-funded project (EUR 1,160,625) and the most technically ambitious — combining continuous-flow peritoneal dialysis with on-board dialysate regeneration and personalisation, targeting a home-use device that could transform chronic kidney disease management.
- WEAKIDAn early-stage clinical validation of a miniature wearable dialysis machine, demonstrating NANODIALYSIS's founding commitment to ambulatory kidney replacement and establishing their track record before CORDIAL.