Core theme across REGiREG (adaptive immune control), TREGeneration (graft-versus-host disease), INsTRuCT (myeloid regulatory cell therapy), and TTV GUIDE TX (post-transplant immunosuppression).
KLINIKUM DER UNIVERSITAET REGENSBURG
German university hospital specializing in transplantation immunology, kidney disease biomarkers, advanced cell therapies, and Europe's leading H2020 tinnitus research program.
Their core work
University Hospital Regensburg is a major German academic medical center that combines clinical care with translational research, particularly in immunology, transplantation medicine, and kidney disease. Their research focuses on understanding immune regulation — how the body's defenses can be tuned to accept transplanted organs, fight cancer, or manage chronic conditions like diabetes-related kidney damage. They bring strong clinical trial infrastructure and biobanking capabilities, bridging the gap between laboratory immunology discoveries and patient-facing treatments. Their work spans from personalized medicine biomarkers to advanced cell-based therapies for organ transplant patients.
What they specialise in
BEAt-DKD focused on diabetic kidney disease biomarkers, TTV GUIDE TX on kidney transplantation monitoring, and REGiREG on immune regulators relevant to renal graft survival.
Recurring theme in BEAt-DKD (predictive biomarkers), UNITI (tinnitus biobank and personalized treatment), PAVE (personalized nanomedicine), and TTV GUIDE TX (viral load monitoring for treatment personalization).
EN_ACTI2NG (CAR/TCR anti-cancer immunotherapy), PAVE (nanovaccine for pancreatic cancer), and INsTRuCT (myeloid cell therapy with oncology applications).
Achilles (tendon regeneration therapies) and MEFISTO (meniscus scaffold to prevent osteoarthritis) represent a newer direction in regenerative medicine.
Coordinated both ESIT (European School for Interdisciplinary Tinnitus Research) and UNITI (unification of tinnitus treatments), positioning Regensburg as a European hub for tinnitus science.
How they've shifted over time
In the early H2020 period (2015–2018), Regensburg concentrated on classical clinical research themes: diabetic kidney disease biomarkers, immune regulation in transplantation, and cancer immunotherapy networks. From 2019 onward, their focus broadened into advanced therapeutic products — cell-based therapies (INsTRuCT), nanovaccines for cancer (PAVE), and tissue engineering for musculoskeletal repair (MEFISTO, Achilles). There is a clear shift from understanding disease mechanisms toward developing and testing next-generation treatments, including ATMPs and personalized nanomedicine.
Regensburg is moving from diagnostic biomarker research toward therapeutic development — particularly cell-based and personalized therapies for transplantation and cancer — making them an increasingly relevant partner for clinical-stage ATMP projects.
How they like to work
Regensburg operates as both a project leader and an experienced consortium partner, coordinating 4 of their 13 projects (31%), which is above average for a clinical institution. They work across 166 unique partners in 27 countries, indicating a broad European network rather than dependence on a few repeat collaborators. Their participation in both large RIA consortia and focused MSCA training networks suggests they are comfortable in diverse project formats and can contribute clinical expertise, patient cohorts, and training infrastructure.
With 166 unique consortium partners across 27 countries, Regensburg maintains one of the broader collaboration networks among German university hospitals. Their reach is pan-European with no obvious geographic concentration, reflecting the international nature of clinical research and training networks.
What sets them apart
Regensburg stands out for its dual strength in transplantation immunology and tinnitus research — an unusual combination that reflects deep, specialist teams rather than generic participation. As a coordinator of both the European tinnitus training school (ESIT) and the tinnitus treatment unification project (UNITI), they are arguably Europe's leading academic center for tinnitus in the H2020 landscape. For transplantation and ATMP partners, they offer the rare combination of immunology expertise, clinical trial infrastructure, and regulatory experience with advanced therapy medicinal products.
Highlights from their portfolio
- REGiREGLargest single grant (EUR 1.5M) and an ERC Consolidator Grant — a mark of individual scientific excellence in adaptive immune regulation.
- UNITICoordinated a EUR 884K effort to unify tinnitus treatments with personalized medicine approaches, building on their earlier ESIT training network — showing strategic long-term investment in this field.
- TREGenerationEUR 1.4M contribution to address chronic graft-versus-host disease after stem cell transplantation, demonstrating their strength in translational transplant immunology.