Both bTB-Test and LeiSHield-MATI explicitly list biomarkers and prognostic/diagnostic tools as core research outputs, confirming diagnostics as IPA's cross-cutting contribution.
INSTITUT PASTEUR D ALGERIE E.P.I.C.
Algerian national public health institute providing endemic disease expertise, patient cohorts, and diagnostics for TB and leishmaniasis research.
Their core work
Institut Pasteur d'Algérie is Algeria's national public health reference laboratory, specializing in infectious disease surveillance, diagnostics, and biological sample collections for diseases endemic to North Africa. In H2020 projects, they contributed as a third-party expert — providing access to patient cohorts, biological specimens, and field expertise for diseases like bovine tuberculosis and leishmaniasis that are difficult to study without an in-country presence. Their scientific work spans from metabolomics-based breath diagnostics to molecular parasitology and immune profiling. For European consortia, they are the on-the-ground gateway to North African disease epidemiology and endemic sample collections that cannot be replicated in EU laboratory settings.
What they specialise in
bTB-Test (2018-2021) focused on volatolomics-based breath and skin headspace diagnostics for bovine TB, a zoonotic disease with high burden in North Africa.
LeiSHield-MATI (2018-2023) addressed clinical, molecular, and social dimensions of leishmaniasis including parasite-vector-host interaction, immune response, and patient psychological impact.
LeiSHield-MATI lists RNAseq and HTseq among its methods, indicating IPA has access to transcriptomic analysis capabilities for infectious disease research.
bTB-Test centred on breath, faeces, and skin headspace analysis using electronic nose technology and metabolomic profiling for non-invasive TB diagnosis.
How they've shifted over time
Both H2020 projects were launched in the same year (2018), so the evolution is more thematic than chronological: the earlier-listed project (bTB-Test) focused on non-invasive metabolomics and volatolomics for veterinary disease detection, while the second (LeiSHield-MATI, running until 2023) moved into molecular biology tools, immune response profiling, and even the psychological burden of chronic disease. This shift suggests IPA is expanding from sample-based analytical diagnostics toward systems-level disease understanding that integrates molecular data with clinical and social outcomes. The persistence of "biomarkers" across both projects confirms diagnostics as their stable core, while the methodological vocabulary grew significantly richer in the more recent work.
IPA appears to be deepening its infectious disease molecular toolkit — moving from physical sample analytics (breath, skin) toward transcriptomic and immunological methods — which positions them for future consortia targeting neglected tropical diseases and One Health research.
How they like to work
IPA has participated exclusively as a third party in H2020, meaning they contribute resources or expertise under another partner's umbrella rather than signing the grant agreement directly. This is typical of institutions in non-EU Associated Countries that provide endemic disease access, patient cohorts, or reference laboratory services to EU-led projects. Their 18 consortium partners across 11 countries, despite only 2 projects, indicates they were embedded in genuinely large international consortia — not small bilateral arrangements. Working with them requires routing their involvement through a primary EU partner, but the value they bring — access to North African disease populations — is otherwise unavailable to European teams.
Despite only two H2020 projects, IPA connected with 18 distinct consortium partners across 11 countries, reflecting participation in large multi-partner MSCA-RISE networks. Their geographic reach extends across Europe and into North Africa, consistent with their role bridging EU research with Algerian field sites.
What sets them apart
IPA is the only Algerian Pasteur Institute affiliate with H2020 project history in this database, making them the singular institutional bridge for EU consortia that need credible access to North African infectious disease cohorts, particularly for TB and leishmaniasis — both endemic in Algeria at a scale not found in EU member states. Their status as a national public health reference laboratory means they can provide not just samples but regulatory legitimacy, existing surveillance infrastructure, and clinical partnerships within Algeria. Consortia building projects on neglected tropical diseases or One Health themes affecting the Mediterranean and Sahel regions should consider IPA as a rare and difficult-to-replicate partner.
Highlights from their portfolio
- LeiSHield-MATIA long-running multi-disciplinary international effort (2018-2023) combining molecular biology, clinical science, and social impact assessment for leishmaniasis — one of the most comprehensive neglected tropical disease projects in H2020.
- bTB-TestApplied volatolomics and electronic nose technology to bovine TB diagnosis — an unusually hardware-forward diagnostic approach for a disease that costs European agriculture hundreds of millions annually.