Core contributor across caLIBRAte, BIORIMA, GRACIOUS, NanoInformaTIX, REFINE, and SUNSHINE — all focused on risk evaluation frameworks for nanomaterials.
GREENDECISION SRL
Venice-based SME building risk assessment and decision support tools for nanomaterial safety, regulatory compliance, and safe-by-design strategies.
Their core work
GreenDecision is a Venice-based SME specializing in risk assessment and decision support systems for nanomaterials and nano-enabled products. They build computational tools — including decision support systems, risk governance frameworks, and web-based platforms — that help regulators, manufacturers, and researchers evaluate the safety of engineered nanomaterials and nano-biomaterials. Their work sits at the intersection of regulatory science and computational modelling, translating complex hazard and exposure data into actionable risk management decisions.
What they specialise in
REFINE, BIORIMA, and SAFE-N-MEDTECH all address regulatory frameworks and safety testing for nanomedicine and medical devices.
NanoInformaTIX, BIORIMA, and SUNSHINE explicitly target safe-by-design and sustainable-by-design approaches.
caLIBRAte (computational toxicology, exposure modelling), NanoInformaTIX (PBPK, QSAR, systems biology models), and SUNSHINE (multi-scale modelling).
GRACIOUS built a grouping/classification framework; NanoInformaTIX and SUNSHINE continued with grouping, read-across, and multi-component nanomaterial classification.
How they've shifted over time
In their early H2020 projects (2016–2018), GreenDecision focused on foundational risk assessment and governance tools — building integrated risk management frameworks, decision support systems, and computational toxicology approaches for nanomaterials (caLIBRAte, BIORIMA, REFINE). From 2019 onward, their work shifted toward multi-scale modelling, nanomaterial grouping and read-across strategies, and safe-and-sustainable-by-design methodologies (GRACIOUS, NanoInformaTIX, SUNSHINE). This evolution shows a clear move from reactive risk evaluation toward proactive, predictive safety design — reducing reliance on animal testing through computational and in-silico approaches.
GreenDecision is moving toward predictive safety platforms for advanced and multi-component nanomaterials, positioning them well for the EU's growing emphasis on safe-and-sustainable-by-design regulation.
How they like to work
GreenDecision operates exclusively as a participant or third party — never as coordinator — which is typical for a specialized SME contributing targeted expertise to large research consortia. With 168 unique partners across 34 countries in just 8 projects, they work in very large consortia (averaging 20+ partners per project), characteristic of the EU nanosafety research community. Their broad partner network and consistent involvement across the major nanosafety projects suggest they are a trusted, well-connected specialist that consortia actively seek out.
Remarkably well-connected for an 8-project SME: 168 unique consortium partners spanning 34 countries, reflecting deep integration into Europe's nanosafety research community. Their network covers nearly all EU member states and associated countries, with strong ties to the major nanosafety research groups and regulatory bodies.
What sets them apart
GreenDecision occupies a rare niche: a private company that builds decision support tools specifically for nanomaterial risk governance — bridging the gap between computational risk science and regulatory decision-making. While many academic groups produce risk assessment research, GreenDecision translates that science into usable platforms and toolboxes for regulators and industry. For any consortium needing a partner who can turn nanosafety data into practical decision-support tools, they are one of very few SMEs in Europe with this specific combination of skills.
Highlights from their portfolio
- SAFE-N-MEDTECHLargest single funding (EUR 558,075) — focused on safety testing across the full lifecycle of nano-enabled medical technologies, combining their regulatory and risk assessment expertise.
- SUNSHINETheir most recent project (2021–2024), targeting safe-and-sustainable-by-design for multi-component nanomaterials — signals their current strategic direction.
- REFINELong-running project (2017–2022) building a regulatory science framework for nano-biomaterial medical products — directly at the intersection of nanomedicine regulation and risk assessment.