IMI-PainCare focuses on acute/chronic pain, deep phenotyping, biomarkers, and patient stratification for optimised pain management.
FUNDACION PARA LA INVESTIGACION DEL HOSPITAL CLINICO DE LA COMUNITAT VALENCIANA, FUNDACION INCLIVA
Valencia university hospital research foundation specialising in clinical trials, personalised oncology, pain research, and AI-driven diagnostics across European consortia.
Their core work
INCLIVA is the research foundation of the Hospital Clínico de Valencia, one of Spain's major university hospitals. They translate clinical research into patient care across oncology, cardiovascular disease, chronic pain, and transplantation medicine. Their strength lies in running large-scale clinical trials, patient stratification using biomarkers and omics data, and integrating big data and AI tools into hospital-based research. They bridge the gap between bedside observation and data-driven personalised medicine, contributing real-world clinical cohorts and expertise to European consortia.
What they specialise in
LEGACy (gastric cancer, omics-based personalised medicine, coordinator role), MoTriColor (molecularly guided treatment), REBECCA (breast cancer chronic conditions), and HUTER (uterine cell atlas) demonstrate sustained cancer research.
BigData Heart targets heart failure and atrial fibrillation using big data; BigMedilytics applies big data technologies to population health management.
CLARIFY applies machine learning and cloud computing to digital pathology; REBECCA uses causal modelling on multi-source real-world data.
DIABFRAIL-LATAM scales diabetes/frailty interventions to Latin America; WELLBASED addresses health inequalities linked to energy poverty.
TTV GUIDE TX runs a phase II clinical trial on personalised immunosuppression after kidney transplantation.
How they've shifted over time
In the early period (2015–2018), INCLIVA focused on cardiovascular big data, healthcare analytics at industrial scale, and foundational pain research — essentially applying large datasets to established clinical domains. From 2019 onward, the focus shifted toward AI-powered diagnostics (digital pathology, machine learning), personalised medicine with omics integration (gastric cancer, transplant immunology), and global health equity (Latin America, energy poverty). The trajectory is clear: from being a clinical data contributor to becoming an active driver of computational and personalised medicine approaches.
INCLIVA is moving toward computational medicine — expect future projects combining clinical trial expertise with AI, real-world data analytics, and precision oncology.
How they like to work
INCLIVA predominantly joins consortia as a clinical partner (10 of 13 projects as participant), contributing patient cohorts, hospital infrastructure, and clinical validation. They have coordinated two projects — LEGACy (international personalised medicine for gastric cancer) and HUTER (their largest single grant at EUR 1.1M for a uterine cell atlas) — showing they can lead when the science aligns with their core clinical strengths. With 196 unique partners across 33 countries, they are a well-connected hub rather than a closed-circle collaborator, making them easy to integrate into new consortia.
INCLIVA has built a broad European and global network of 196 unique consortium partners spanning 33 countries, reflecting both EU-wide health research consortia and targeted collaborations with Latin American institutions (DIABFRAIL-LATAM). Their network is notably diverse for a hospital-based research foundation.
What sets them apart
INCLIVA offers something many research institutes cannot: direct access to a large university hospital's clinical infrastructure, patient populations, and practicing physicians, combined with growing computational capacity. For consortium builders, this means they can recruit patients for clinical trials, validate AI tools in a real hospital setting, and provide the clinical endpoints that technology-focused partners need. Their dual track in both traditional clinical research (pain, cardiovascular, oncology) and emerging digital health makes them a versatile clinical anchor for projects that need to prove real-world impact.
Highlights from their portfolio
- HUTERLargest single EC grant (EUR 1.1M) and coordinator role — a human uterine cell atlas project showing INCLIVA can lead ambitious basic-to-translational science.
- LEGACyCoordinator of a EU-Latin America consortium on personalised gastric cancer medicine, demonstrating capacity to lead international clinical research beyond Europe.
- BigMedilyticsLargest overall funding received (EUR 1.06M) in a flagship big data in healthcare project, positioning INCLIVA as a serious clinical partner for health data innovation.