ORTHOUNION focused on expanded bone marrow mesenchymal stem cells and bioceramics for long bone fracture non-union and femoral head avascular necrosis.
FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO PUERTA DE HIERRO-MAJADAHONDA
Madrid university hospital foundation providing clinical data, patient cohorts, and trial sites for European biomedical and digital health research.
Their core work
This is the biomedical research foundation of Hospital Universitario Puerta de Hierro, a major public teaching hospital near Madrid. They contribute clinical expertise, patient cohorts, and real-world medical data to European research consortia — particularly in orthopedic regenerative medicine and oncology follow-up care. Their role is typically as a clinical site providing patient access, medical validation, and health data for multi-centre trials and data-driven health platforms. They bridge the gap between laboratory research and hospital-based clinical application.
What they specialise in
CLARIFY applied AI to follow-up care for breast cancer, lung cancer, and lymphoma survivors.
IASIS and CUREX both required hospital-sourced patient data for precision medicine analytics and secure health data exchange.
CUREX addressed secure and private health data exchange, indicating the hospital's engagement with data governance in clinical settings.
How they've shifted over time
Their early H2020 involvement (2017) centred on regenerative medicine — specifically bone marrow stem cell therapies and multi-centre clinical trials for orthopedic conditions. By 2018-2020, the focus shifted decisively toward data-intensive health applications: precision medicine platforms, secure health data exchange, and AI-driven cancer survivorship care. This mirrors the broader hospital sector trend of moving from traditional clinical trials toward digital health and AI-assisted patient management.
Moving toward AI and data science applications in oncology follow-up, making them a relevant clinical partner for digital health and cancer informatics projects.
How they like to work
They participate exclusively as a third party — providing clinical infrastructure, patient data, and medical expertise to consortia led by others. This is characteristic of hospital research foundations that contribute real-world clinical validation rather than leading project design. With 50 unique partners across 14 countries from just 4 projects, they integrate into large, diverse consortia and are comfortable operating within complex multi-site research networks.
Connected to 50 unique partners across 14 countries through large RIA consortia. Their network spans broadly across Europe, reflecting the multi-centre clinical trial and health data integration projects they contribute to.
What sets them apart
As a major Madrid-area university hospital foundation, they offer something many research institutes cannot: direct access to diverse patient populations, clinical workflows, and real hospital data in a controlled, ethics-approved environment. For any consortium needing a Spanish clinical site with experience in both traditional multi-centre trials and modern health data platforms, they are a proven third-party contributor. Their dual track record in regenerative medicine trials and digital health data projects makes them versatile across clinical research domains.
Highlights from their portfolio
- ORTHOUNIONRandomized clinical trial using regulatory-approved stem cell therapy for bone conditions — represents their strongest clinical trial expertise.
- CLARIFYApplies AI to cancer survivorship follow-up across breast, lung cancer, and lymphoma — signals their move into digital oncology and long-term patient monitoring.